Surface chemistry governs cellular tropism of nanoparticles in the brain
There have been numerous attempts to develop nanomaterials to reach cells of the central nervous system for drug delivery. Here, the authors investigate the cellular fate of polymer-based nanoparticles with varying surface chemistries after administration directly into the brain.
Main Authors: | Eric Song, Alice Gaudin, Amanda R. King, Young-Eun Seo, Hee-Won Suh, Yang Deng, Jiajia Cui, Gregory T. Tietjen, Anita Huttner, W. Mark Saltzman |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2017-05-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms15322 |
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