Granuloma debridement and the use of an injectable calcium phosphate bone cement in the treatment of osteolysis in an uncemented total knee replacement

<p>Abstract</p> <p>Polyethylene particulate debris-induced periprosthetic osteolysis is a known complication of knee arthroplasty surgery, and may result in the need for revision surgery. The management of these bony defects can be surgically challenging, and full revisions of well...

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Main Authors: Ranawat Vijai S, Atkinson Henry D, Oakeshott Roger D
Format: Article
Language:English
Published: BMC 2010-04-01
Series:Journal of Orthopaedic Surgery and Research
Online Access:http://www.josr-online.com/content/5/1/29
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author Ranawat Vijai S
Atkinson Henry D
Oakeshott Roger D
author_facet Ranawat Vijai S
Atkinson Henry D
Oakeshott Roger D
author_sort Ranawat Vijai S
collection DOAJ
description <p>Abstract</p> <p>Polyethylene particulate debris-induced periprosthetic osteolysis is a known complication of knee arthroplasty surgery, and may result in the need for revision surgery. The management of these bony defects can be surgically challenging, and full revisions of well-fixed total knee components can lead to substantial bone loss. We present the case of a 71 year old man who developed knee pain and osteolysis around an uncemented total knee replacement. Due to significant medical comorbidies he was treated by percutaneous cyst granuloma debridement and grafting using an injectable calcium phosphate bone substitute. There were no wound complications, and the patient was allowed to fully weight-bear post-operatively. Histopathology and microbiology of the cyst material confirmed polyethylene granulomata without any evidence of infection. At 6 weeks post-operatively the patient's previous knee pain had resolved, he was able to comfortably fully weight-bear. Preoperative scores (Knee Society Score (KSS) 41, WOMAC score 46.2, and Oxford Knee Score 39) had all improved at the 12-month post-operative review KSS 76, WOMAC 81.7 and Oxford Knee score 21). This is a safe and effective technique with minimal morbidity and may be an appropriate treatment modality when more extensive revision surgery is not possible. The case is discussed with reference to the literature.</p>
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spelling doaj.art-4fbfc614cec84446891487527672e18d2022-12-22T04:22:40ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2010-04-01512910.1186/1749-799X-5-29Granuloma debridement and the use of an injectable calcium phosphate bone cement in the treatment of osteolysis in an uncemented total knee replacementRanawat Vijai SAtkinson Henry DOakeshott Roger D<p>Abstract</p> <p>Polyethylene particulate debris-induced periprosthetic osteolysis is a known complication of knee arthroplasty surgery, and may result in the need for revision surgery. The management of these bony defects can be surgically challenging, and full revisions of well-fixed total knee components can lead to substantial bone loss. We present the case of a 71 year old man who developed knee pain and osteolysis around an uncemented total knee replacement. Due to significant medical comorbidies he was treated by percutaneous cyst granuloma debridement and grafting using an injectable calcium phosphate bone substitute. There were no wound complications, and the patient was allowed to fully weight-bear post-operatively. Histopathology and microbiology of the cyst material confirmed polyethylene granulomata without any evidence of infection. At 6 weeks post-operatively the patient's previous knee pain had resolved, he was able to comfortably fully weight-bear. Preoperative scores (Knee Society Score (KSS) 41, WOMAC score 46.2, and Oxford Knee Score 39) had all improved at the 12-month post-operative review KSS 76, WOMAC 81.7 and Oxford Knee score 21). This is a safe and effective technique with minimal morbidity and may be an appropriate treatment modality when more extensive revision surgery is not possible. The case is discussed with reference to the literature.</p>http://www.josr-online.com/content/5/1/29
spellingShingle Ranawat Vijai S
Atkinson Henry D
Oakeshott Roger D
Granuloma debridement and the use of an injectable calcium phosphate bone cement in the treatment of osteolysis in an uncemented total knee replacement
Journal of Orthopaedic Surgery and Research
title Granuloma debridement and the use of an injectable calcium phosphate bone cement in the treatment of osteolysis in an uncemented total knee replacement
title_full Granuloma debridement and the use of an injectable calcium phosphate bone cement in the treatment of osteolysis in an uncemented total knee replacement
title_fullStr Granuloma debridement and the use of an injectable calcium phosphate bone cement in the treatment of osteolysis in an uncemented total knee replacement
title_full_unstemmed Granuloma debridement and the use of an injectable calcium phosphate bone cement in the treatment of osteolysis in an uncemented total knee replacement
title_short Granuloma debridement and the use of an injectable calcium phosphate bone cement in the treatment of osteolysis in an uncemented total knee replacement
title_sort granuloma debridement and the use of an injectable calcium phosphate bone cement in the treatment of osteolysis in an uncemented total knee replacement
url http://www.josr-online.com/content/5/1/29
work_keys_str_mv AT ranawatvijais granulomadebridementandtheuseofaninjectablecalciumphosphatebonecementinthetreatmentofosteolysisinanuncementedtotalkneereplacement
AT atkinsonhenryd granulomadebridementandtheuseofaninjectablecalciumphosphatebonecementinthetreatmentofosteolysisinanuncementedtotalkneereplacement
AT oakeshottrogerd granulomadebridementandtheuseofaninjectablecalciumphosphatebonecementinthetreatmentofosteolysisinanuncementedtotalkneereplacement