Multi-triazole-resistant Aspergillus fumigatus and SARS-CoV-2 co-infection: A lethal combination
We report a case of severe COVID-19 pneumonia complicated by fatal co-infection with a multi-triazole resistant Aspergillus fumigatus and highlight the importance of recognising the significance of Aspergillus sp. isolation from respiratory samples. Early diagnosis and detection of triazole resistan...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-03-01
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| Series: | Medical Mycology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211753920300427 |
| _version_ | 1818875762442240000 |
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| author | Aia Mohamed Tidi Hassan Marta Trzos-Grzybowska Jubil Thomas Aidan Quinn Maire O'Sullivan Auveen Griffin Thomas R. Rogers Alida Fe Talento |
| author_facet | Aia Mohamed Tidi Hassan Marta Trzos-Grzybowska Jubil Thomas Aidan Quinn Maire O'Sullivan Auveen Griffin Thomas R. Rogers Alida Fe Talento |
| author_sort | Aia Mohamed |
| collection | DOAJ |
| description | We report a case of severe COVID-19 pneumonia complicated by fatal co-infection with a multi-triazole resistant Aspergillus fumigatus and highlight the importance of recognising the significance of Aspergillus sp. isolation from respiratory samples. Early diagnosis and detection of triazole resistance are essential for appropriate antifungal therapy to improve outcome in patients with coronavirus associated invasive aspergillosis. |
| first_indexed | 2024-12-19T13:31:39Z |
| format | Article |
| id | doaj.art-4fc027bef2394bdb9580f8614a98a91f |
| institution | Directory Open Access Journal |
| issn | 2211-7539 |
| language | English |
| last_indexed | 2024-12-19T13:31:39Z |
| publishDate | 2021-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Medical Mycology Case Reports |
| spelling | doaj.art-4fc027bef2394bdb9580f8614a98a91f2022-12-21T20:19:21ZengElsevierMedical Mycology Case Reports2211-75392021-03-01311114Multi-triazole-resistant Aspergillus fumigatus and SARS-CoV-2 co-infection: A lethal combinationAia Mohamed0Tidi Hassan1Marta Trzos-Grzybowska2Jubil Thomas3Aidan Quinn4Maire O'Sullivan5Auveen Griffin6Thomas R. Rogers7Alida Fe Talento8Department of Microbiology, Our Lady of Lourdes Hospital Drogheda, Co. Louth, IrelandDepartment of Medicine, Our Lady of Lourdes Hospital Drogheda, Co. Louth, IrelandDepartment of Microbiology, Our Lady of Lourdes Hospital Drogheda, Co. Louth, IrelandDepartment of Anaesthesia and Intensive Care, Our Lady of Lourdes Hospital Drogheda, Co. Louth, IrelandDepartment of Radiology, Our Lady of Lourdes Hospital Drogheda, Co. Louth, IrelandDepartment of Microbiology, St. James's Hospital, Dublin, Ireland; Deparment of Clinical Microbiology, Trinity College Dublin, Dublin, IrelandDepartment of Microbiology, St. James's Hospital, Dublin, IrelandDepartment of Microbiology, St. James's Hospital, Dublin, Ireland; Deparment of Clinical Microbiology, Trinity College Dublin, Dublin, IrelandDepartment of Microbiology, Our Lady of Lourdes Hospital Drogheda, Co. Louth, Ireland; Department of Microbiology, Royal College of Surgeons, Ireland, Dublin, Ireland; Corresponding author. Department of Microbiology, Our Lady of Lourdes Hospital Drogheda, Co. Louth, Ireland.We report a case of severe COVID-19 pneumonia complicated by fatal co-infection with a multi-triazole resistant Aspergillus fumigatus and highlight the importance of recognising the significance of Aspergillus sp. isolation from respiratory samples. Early diagnosis and detection of triazole resistance are essential for appropriate antifungal therapy to improve outcome in patients with coronavirus associated invasive aspergillosis.http://www.sciencedirect.com/science/article/pii/S2211753920300427COVID-19 pneumoniaInvasive pulmonary aspergillosisMulti-triazole resistance |
| spellingShingle | Aia Mohamed Tidi Hassan Marta Trzos-Grzybowska Jubil Thomas Aidan Quinn Maire O'Sullivan Auveen Griffin Thomas R. Rogers Alida Fe Talento Multi-triazole-resistant Aspergillus fumigatus and SARS-CoV-2 co-infection: A lethal combination Medical Mycology Case Reports COVID-19 pneumonia Invasive pulmonary aspergillosis Multi-triazole resistance |
| title | Multi-triazole-resistant Aspergillus fumigatus and SARS-CoV-2 co-infection: A lethal combination |
| title_full | Multi-triazole-resistant Aspergillus fumigatus and SARS-CoV-2 co-infection: A lethal combination |
| title_fullStr | Multi-triazole-resistant Aspergillus fumigatus and SARS-CoV-2 co-infection: A lethal combination |
| title_full_unstemmed | Multi-triazole-resistant Aspergillus fumigatus and SARS-CoV-2 co-infection: A lethal combination |
| title_short | Multi-triazole-resistant Aspergillus fumigatus and SARS-CoV-2 co-infection: A lethal combination |
| title_sort | multi triazole resistant aspergillus fumigatus and sars cov 2 co infection a lethal combination |
| topic | COVID-19 pneumonia Invasive pulmonary aspergillosis Multi-triazole resistance |
| url | http://www.sciencedirect.com/science/article/pii/S2211753920300427 |
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