HCV-Induced Immunometabolic Crosstalk in a Triple-Cell Co-Culture Model Capable of Simulating Systemic Iron Homeostasis

HCV-Induced Immunometabolic Crosstalk in a Triple-Cell Co-Culture Model Capable of Simulating Systemic Iron Homeostasis

Iron is crucial to the regulation of the host innate immune system and the outcome of many infections. Hepatitis C virus (HCV), one of the major viral human pathogens that depends on iron to complete its life cycle, is highly skilled in evading the immune system. This study presents the construction...

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Bibliographic Details
Main Authors: Pelagia Foka, Alexios Dimitriadis, Eirini Karamichali, Emmanouil Kochlios, Petros Eliadis, Vaia Valiakou, John Koskinas, Avgi Mamalaki, Urania Georgopoulou
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
iron
hepcidin
HCV
innate immunity
cytokines
co-culture
Online Access:https://www.mdpi.com/2073-4409/10/9/2251

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