Rapid prototyping and design of cybergenetic single-cell controllers
Practical implementation of genetic circuits is difficult due to low predictability and time-intensive troubleshooting. Here the authors present Cyberloop, which interfaces a computer with single cells to enable cell-in-the-loop testing and optimization of circuit designs before they are built.
Main Authors: | Sant Kumar, Marc Rullan, Mustafa Khammash |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-09-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-25754-6 |
Similar Items
-
Dynamic cybergenetic control of bacterial co-culture composition via optogenetic feedback
by: Joaquín Gutiérrez Mena, et al.
Published: (2022-08-01) -
A cybergenetic framework for engineering intein-mediated integral feedback control systems
by: Stanislav Anastassov, et al.
Published: (2023-03-01) -
Cybergenetic control of microbial community composition
by: Ting An Lee, et al.
Published: (2022-10-01) -
Exploiting natural chemical photosensitivity of anhydrotetracycline and tetracycline for dynamic and setpoint chemo-optogenetic control
by: Armin Baumschlager, et al.
Published: (2020-07-01) -
Platforms for Optogenetic Stimulation and Feedback Control
by: Sant Kumar, et al.
Published: (2022-06-01)