Mitochondrial Iron Transport and Homeostasis in Plants
Iron (Fe) is an essential nutrient for plants and although the mechanisms controlling iron uptake from the soil are relatively well understood, comparatively little is known about subcellular trafficking of iron in plant cells. Mitochondria represent a significant iron sink within cells, as iron is...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2013-09-01
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| Series: | Frontiers in Plant Science |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fpls.2013.00348/full |
| _version_ | 1818120257808629760 |
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| author | Anshika eJain Erin L Connolly |
| author_facet | Anshika eJain Erin L Connolly |
| author_sort | Anshika eJain |
| collection | DOAJ |
| description | Iron (Fe) is an essential nutrient for plants and although the mechanisms controlling iron uptake from the soil are relatively well understood, comparatively little is known about subcellular trafficking of iron in plant cells. Mitochondria represent a significant iron sink within cells, as iron is required for the proper functioning of respiratory chain protein complexes. Mitochondria are a site of Fe-S cluster synthesis, and possibly heme synthesis as well. Here we review recent insights into the molecular mechanisms controlling mitochondrial iron transport and homeostasis. We focus on the recent identification of a mitochondrial iron uptake transporter in rice and a possible role for metalloreductases in iron uptake by mitochondria. In addition, we highlight recent advances in mitochondrial iron homeostasis with an emphasis on the roles of frataxin and ferritin in iron trafficking and storage within mitochondria. |
| first_indexed | 2024-12-11T05:23:13Z |
| format | Article |
| id | doaj.art-4fcf5ec48ce549578ea8c357f8525f9d |
| institution | Directory Open Access Journal |
| issn | 1664-462X |
| language | English |
| last_indexed | 2024-12-11T05:23:13Z |
| publishDate | 2013-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Plant Science |
| spelling | doaj.art-4fcf5ec48ce549578ea8c357f8525f9d2022-12-22T01:19:39ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2013-09-01410.3389/fpls.2013.0034858233Mitochondrial Iron Transport and Homeostasis in PlantsAnshika eJain0Erin L Connolly1University of South CarolinaUniversity of South CarolinaIron (Fe) is an essential nutrient for plants and although the mechanisms controlling iron uptake from the soil are relatively well understood, comparatively little is known about subcellular trafficking of iron in plant cells. Mitochondria represent a significant iron sink within cells, as iron is required for the proper functioning of respiratory chain protein complexes. Mitochondria are a site of Fe-S cluster synthesis, and possibly heme synthesis as well. Here we review recent insights into the molecular mechanisms controlling mitochondrial iron transport and homeostasis. We focus on the recent identification of a mitochondrial iron uptake transporter in rice and a possible role for metalloreductases in iron uptake by mitochondria. In addition, we highlight recent advances in mitochondrial iron homeostasis with an emphasis on the roles of frataxin and ferritin in iron trafficking and storage within mitochondria.http://journal.frontiersin.org/Journal/10.3389/fpls.2013.00348/fullIronMitochondriaplantiron transporterferritinfrataxin |
| spellingShingle | Anshika eJain Erin L Connolly Mitochondrial Iron Transport and Homeostasis in Plants Frontiers in Plant Science Iron Mitochondria plant iron transporter ferritin frataxin |
| title | Mitochondrial Iron Transport and Homeostasis in Plants |
| title_full | Mitochondrial Iron Transport and Homeostasis in Plants |
| title_fullStr | Mitochondrial Iron Transport and Homeostasis in Plants |
| title_full_unstemmed | Mitochondrial Iron Transport and Homeostasis in Plants |
| title_short | Mitochondrial Iron Transport and Homeostasis in Plants |
| title_sort | mitochondrial iron transport and homeostasis in plants |
| topic | Iron Mitochondria plant iron transporter ferritin frataxin |
| url | http://journal.frontiersin.org/Journal/10.3389/fpls.2013.00348/full |
| work_keys_str_mv | AT anshikaejain mitochondrialirontransportandhomeostasisinplants AT erinlconnolly mitochondrialirontransportandhomeostasisinplants |