Research Advances in Ultrasound Imaging for Tumor in Situ
Known for being highly sensitive and noninvasive, ultrasound imaging using microbubble contrast agents is widely used in the clinic. To use ultrasound to image tissue beyond the vasculature, researchers have developed strategies that include nanobubbles, ultrasound contrast agents generated in situ,...
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| Format: | Article |
| Language: | English |
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Editorial Office of Advanced Ultrasound in Diagnosis and Therapy
2020-09-01
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| Series: | Advanced Ultrasound in Diagnosis and Therapy |
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| Online Access: | http://www.journaladvancedultrasound.com:81/fileup/2576-2516/PDF/1597831386198-1410773423.pdf |
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| author | Ping Wang, MD, Lihong Sun, PhD, Suhui Sun, MD, Menghong Xu, MD, Lulu Zhang, MD, Jinxia Zhang, MD, Liquan Gao, PhD, Qingfeng Chen, PhD, Xiaolong Liang, PhD |
| author_facet | Ping Wang, MD, Lihong Sun, PhD, Suhui Sun, MD, Menghong Xu, MD, Lulu Zhang, MD, Jinxia Zhang, MD, Liquan Gao, PhD, Qingfeng Chen, PhD, Xiaolong Liang, PhD |
| author_sort | Ping Wang, MD, Lihong Sun, PhD, Suhui Sun, MD, Menghong Xu, MD, Lulu Zhang, MD, Jinxia Zhang, MD, Liquan Gao, PhD, Qingfeng Chen, PhD, Xiaolong Liang, PhD |
| collection | DOAJ |
| description | Known for being highly sensitive and noninvasive, ultrasound imaging using microbubble contrast agents is widely used in the clinic. To use ultrasound to image tissue beyond the vasculature, researchers have developed strategies that include nanobubbles, ultrasound contrast agents generated in situ, and gene expression of ultrasound contrast agents in situ. All of these strategies offer the capability of targeting tumor cells, intratumoral imaging tumor cells and require just a small incision or no incision. In this review, we will first describe the application of nanobubbles acting as ultrasound contrast agents. Then, we will briefly introduce the stimuli-responsive formulations to generate ultrasound contrast agents in situ. Finally, we will provide an overview of the use of state-of-the-art of gene expression of ultrasound contrast agents in situ to monitor cellular location and function inside living organisms. |
| first_indexed | 2024-12-17T00:13:25Z |
| format | Article |
| id | doaj.art-4fd1febd727f465e9c82df0855020485 |
| institution | Directory Open Access Journal |
| issn | 2576-2516 |
| language | English |
| last_indexed | 2024-12-17T00:13:25Z |
| publishDate | 2020-09-01 |
| publisher | Editorial Office of Advanced Ultrasound in Diagnosis and Therapy |
| record_format | Article |
| series | Advanced Ultrasound in Diagnosis and Therapy |
| spelling | doaj.art-4fd1febd727f465e9c82df08550204852022-12-21T22:10:46ZengEditorial Office of Advanced Ultrasound in Diagnosis and TherapyAdvanced Ultrasound in Diagnosis and Therapy2576-25162020-09-014316917510.37015/AUDT.2020.190040Research Advances in Ultrasound Imaging for Tumor in SituPing Wang, MD, Lihong Sun, PhD, Suhui Sun, MD, Menghong Xu, MD, Lulu Zhang, MD, Jinxia Zhang, MD, Liquan Gao, PhD, Qingfeng Chen, PhD, Xiaolong Liang, PhD0a Department of Ultrasound, Peking University Third Hospital, Beijing, China;b Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore, SingaporeKnown for being highly sensitive and noninvasive, ultrasound imaging using microbubble contrast agents is widely used in the clinic. To use ultrasound to image tissue beyond the vasculature, researchers have developed strategies that include nanobubbles, ultrasound contrast agents generated in situ, and gene expression of ultrasound contrast agents in situ. All of these strategies offer the capability of targeting tumor cells, intratumoral imaging tumor cells and require just a small incision or no incision. In this review, we will first describe the application of nanobubbles acting as ultrasound contrast agents. Then, we will briefly introduce the stimuli-responsive formulations to generate ultrasound contrast agents in situ. Finally, we will provide an overview of the use of state-of-the-art of gene expression of ultrasound contrast agents in situ to monitor cellular location and function inside living organisms.http://www.journaladvancedultrasound.com:81/fileup/2576-2516/PDF/1597831386198-1410773423.pdf|ultrasound contrast agents|nanobubbles|gene expression|ultrasound |
| spellingShingle | Ping Wang, MD, Lihong Sun, PhD, Suhui Sun, MD, Menghong Xu, MD, Lulu Zhang, MD, Jinxia Zhang, MD, Liquan Gao, PhD, Qingfeng Chen, PhD, Xiaolong Liang, PhD Research Advances in Ultrasound Imaging for Tumor in Situ Advanced Ultrasound in Diagnosis and Therapy |ultrasound contrast agents|nanobubbles|gene expression|ultrasound |
| title | Research Advances in Ultrasound Imaging for Tumor in Situ |
| title_full | Research Advances in Ultrasound Imaging for Tumor in Situ |
| title_fullStr | Research Advances in Ultrasound Imaging for Tumor in Situ |
| title_full_unstemmed | Research Advances in Ultrasound Imaging for Tumor in Situ |
| title_short | Research Advances in Ultrasound Imaging for Tumor in Situ |
| title_sort | research advances in ultrasound imaging for tumor in situ |
| topic | |ultrasound contrast agents|nanobubbles|gene expression|ultrasound |
| url | http://www.journaladvancedultrasound.com:81/fileup/2576-2516/PDF/1597831386198-1410773423.pdf |
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