Comprehensive proteomic analysis of JC polyomavirus-infected human astrocytes and their extracellular vesicles

Comprehensive proteomic analysis of JC polyomavirus-infected human astrocytes and their extracellular vesicles

ABSTRACT JC polyomavirus (JCPyV) is an opportunistic virus that remains in a latent state in the kidneys and lymphoid organs of more than half of the human adult population. In rare cases of severe immune suppression, the virus is able to establish a lytic infection of glial cells in the brain, resu...

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Main Authors: Larise Oberholster, Amandine Mathias, Sylvain Perriot, Emma Blaser, Mathieu Canales, Samuel Jones, Lucas Culebras, Marie Gimenez, G. Campbell Kaynor, Alexey Sapozhnik, Kevin Richetin, Susan Goelz, Renaud Du Pasquier
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:Microbiology Spectrum
Subjects:
hiPSC
astrocytes
model
JCPyV
extracellular vesicles
PML
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02751-23

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