Distribution of HLA antigents in Turkman race
The Turkmans are one of the Iranian ethnic population. HLA typing (class I and II) was performed in this population. The data obtained from this study was compared with different populations of the world. We observed that the Turkman population is most similar to the Northern chinese and Uigur popul...
| Main Authors: | , , |
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| Format: | Article |
| Language: | fas |
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Tehran University of Medical Sciences
1995-04-01
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| Series: | Tehran University Medical Journal |
| Online Access: | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/5940.pdf&manuscript_id=5940 |
| _version_ | 1818790713103482880 |
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| author | Mohyeddin M Khosravi F Nikbin B |
| author_facet | Mohyeddin M Khosravi F Nikbin B |
| author_sort | Mohyeddin M |
| collection | DOAJ |
| description | The Turkmans are one of the Iranian ethnic population. HLA typing (class I and II) was performed in this population. The data obtained from this study was compared with different populations of the world. We observed that the Turkman population is most similar to the Northern chinese and Uigur population. The distributions of HLA antigens in Turkmans are somewhat between Iranian population, Northern chinese and Uigur population. Natural selection and gene alteration select the people who could better adopt themselves with new conditions. Investigation of Turkman's HLA in comparison with Iranian's HLA reveals more details in genetics of Behcet's disease. Behcet's disease is very rare in Turkmans (index 0.5) whereas its frequency is high in other Iranians and Northern chinese. Distribution of susceptible antigens like B5 is the same in Turkmans and Northern chinese (19.5%) but much higher in other Iranians, whereas B35 have almost the same distribution in Turkmans and Iranians (37% and 33% respectively). DQW1 and CW4 antigens which were suspected to have a negative association with Behcet's disease are the most frequent antigens in Turkmans. |
| first_indexed | 2024-12-18T14:59:49Z |
| format | Article |
| id | doaj.art-4fd96abf611141ff8b79cf4254a02e8e |
| institution | Directory Open Access Journal |
| issn | 1683-1764 1735-7322 |
| language | fas |
| last_indexed | 2024-12-18T14:59:49Z |
| publishDate | 1995-04-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Tehran University Medical Journal |
| spelling | doaj.art-4fd96abf611141ff8b79cf4254a02e8e2022-12-21T21:03:56ZfasTehran University of Medical SciencesTehran University Medical Journal1683-17641735-73221995-04-015313135Distribution of HLA antigents in Turkman raceMohyeddin MKhosravi FNikbin BThe Turkmans are one of the Iranian ethnic population. HLA typing (class I and II) was performed in this population. The data obtained from this study was compared with different populations of the world. We observed that the Turkman population is most similar to the Northern chinese and Uigur population. The distributions of HLA antigens in Turkmans are somewhat between Iranian population, Northern chinese and Uigur population. Natural selection and gene alteration select the people who could better adopt themselves with new conditions. Investigation of Turkman's HLA in comparison with Iranian's HLA reveals more details in genetics of Behcet's disease. Behcet's disease is very rare in Turkmans (index 0.5) whereas its frequency is high in other Iranians and Northern chinese. Distribution of susceptible antigens like B5 is the same in Turkmans and Northern chinese (19.5%) but much higher in other Iranians, whereas B35 have almost the same distribution in Turkmans and Iranians (37% and 33% respectively). DQW1 and CW4 antigens which were suspected to have a negative association with Behcet's disease are the most frequent antigens in Turkmans.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/5940.pdf&manuscript_id=5940 |
| spellingShingle | Mohyeddin M Khosravi F Nikbin B Distribution of HLA antigents in Turkman race Tehran University Medical Journal |
| title | Distribution of HLA antigents in Turkman race |
| title_full | Distribution of HLA antigents in Turkman race |
| title_fullStr | Distribution of HLA antigents in Turkman race |
| title_full_unstemmed | Distribution of HLA antigents in Turkman race |
| title_short | Distribution of HLA antigents in Turkman race |
| title_sort | distribution of hla antigents in turkman race |
| url | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/5940.pdf&manuscript_id=5940 |
| work_keys_str_mv | AT mohyeddinm distributionofhlaantigentsinturkmanrace AT khosravif distributionofhlaantigentsinturkmanrace AT nikbinb distributionofhlaantigentsinturkmanrace |