Arouse potential stemness: Intrinsic and acquired stem cell therapeutic strategies for advanced liver diseases

Liver diseases are a major health issue, and prolonged liver injury always progresses. Advanced liver disorders impair liver regeneration. Millions of patients die yearly worldwide, even with the available treatments of liver transplantation and artificial liver support system. With its abundant cel...

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Bibliographic Details
Main Authors: Yisu Song, Zhengyang Lu, Wenzhi Shu, Ze Xiang, Zhengxin Wang, Xuyong Wei, Xiao Xu
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Cell Insight
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772892723000391
Description
Summary:Liver diseases are a major health issue, and prolonged liver injury always progresses. Advanced liver disorders impair liver regeneration. Millions of patients die yearly worldwide, even with the available treatments of liver transplantation and artificial liver support system. With its abundant cell resources and significant differentiative potential, stem cell therapy is a viable treatment for various disorders and offers hope to patients waiting for orthotopic liver transplantation. Moreover, we conclude intrinsic and acquired perspectives based on stem cell sources. The properties and therapeutic uses of these stem cells' specific types or sources were then reviewed. Owing to the recent investigations of the above cells, a safe and effective therapy will emerge for advanced liver diseases soon.
ISSN:2772-8927