Arouse potential stemness: Intrinsic and acquired stem cell therapeutic strategies for advanced liver diseases
Liver diseases are a major health issue, and prolonged liver injury always progresses. Advanced liver disorders impair liver regeneration. Millions of patients die yearly worldwide, even with the available treatments of liver transplantation and artificial liver support system. With its abundant cel...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-10-01
|
| Series: | Cell Insight |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772892723000391 |
| _version_ | 1797630967532224512 |
|---|---|
| author | Yisu Song Zhengyang Lu Wenzhi Shu Ze Xiang Zhengxin Wang Xuyong Wei Xiao Xu |
| author_facet | Yisu Song Zhengyang Lu Wenzhi Shu Ze Xiang Zhengxin Wang Xuyong Wei Xiao Xu |
| author_sort | Yisu Song |
| collection | DOAJ |
| description | Liver diseases are a major health issue, and prolonged liver injury always progresses. Advanced liver disorders impair liver regeneration. Millions of patients die yearly worldwide, even with the available treatments of liver transplantation and artificial liver support system. With its abundant cell resources and significant differentiative potential, stem cell therapy is a viable treatment for various disorders and offers hope to patients waiting for orthotopic liver transplantation. Moreover, we conclude intrinsic and acquired perspectives based on stem cell sources. The properties and therapeutic uses of these stem cells' specific types or sources were then reviewed. Owing to the recent investigations of the above cells, a safe and effective therapy will emerge for advanced liver diseases soon. |
| first_indexed | 2024-03-11T11:15:24Z |
| format | Article |
| id | doaj.art-4fda4af5caea4444a1e0f14cf989e5b7 |
| institution | Directory Open Access Journal |
| issn | 2772-8927 |
| language | English |
| last_indexed | 2024-03-11T11:15:24Z |
| publishDate | 2023-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Cell Insight |
| spelling | doaj.art-4fda4af5caea4444a1e0f14cf989e5b72023-11-11T04:28:49ZengElsevierCell Insight2772-89272023-10-0125100115Arouse potential stemness: Intrinsic and acquired stem cell therapeutic strategies for advanced liver diseasesYisu Song0Zhengyang Lu1Wenzhi Shu2Ze Xiang3Zhengxin Wang4Xuyong Wei5Xiao Xu6Department of Hepatobiliary and Pancreatic Surgery Affiliated Hangzhou First People’s Hospital Zhejiang University School of Medicine Hangzhou, Zhejiang, 310006, China; Zhejiang University School of Medicine, Hangzhou, China; Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Hangzhou, 310006, ChinaDepartment of Hepatobiliary and Pancreatic Surgery Affiliated Hangzhou First People’s Hospital Zhejiang University School of Medicine Hangzhou, Zhejiang, 310006, China; Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Hangzhou, 310006, China; Zhejiang Chinese Medical University, Hangzhou, 310053, PR ChinaDepartment of Hepatobiliary and Pancreatic Surgery Affiliated Hangzhou First People’s Hospital Zhejiang University School of Medicine Hangzhou, Zhejiang, 310006, China; Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Hangzhou, 310006, ChinaZhejiang University School of Medicine, Hangzhou, ChinaDepartment of General Surgery, Huashan Hospital, Fudan University Shanghai, 200040, ChinaDepartment of Hepatobiliary and Pancreatic Surgery Affiliated Hangzhou First People’s Hospital Zhejiang University School of Medicine Hangzhou, Zhejiang, 310006, China; Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Hangzhou, 310006, China; Corresponding author. Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Hangzhou, 310006, China.Zhejiang University School of Medicine, Hangzhou, China; Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Hangzhou, 310006, China; Institute of Organ Transplantation, Zhejiang University, Hangzhou, 310003, China; Corresponding author. Zhejiang University School of Medicine, Hangzhou, China.Liver diseases are a major health issue, and prolonged liver injury always progresses. Advanced liver disorders impair liver regeneration. Millions of patients die yearly worldwide, even with the available treatments of liver transplantation and artificial liver support system. With its abundant cell resources and significant differentiative potential, stem cell therapy is a viable treatment for various disorders and offers hope to patients waiting for orthotopic liver transplantation. Moreover, we conclude intrinsic and acquired perspectives based on stem cell sources. The properties and therapeutic uses of these stem cells' specific types or sources were then reviewed. Owing to the recent investigations of the above cells, a safe and effective therapy will emerge for advanced liver diseases soon.http://www.sciencedirect.com/science/article/pii/S2772892723000391Stem cellIntrinsicAcquiredAdvanced liver diseasesTherapeutic strategy |
| spellingShingle | Yisu Song Zhengyang Lu Wenzhi Shu Ze Xiang Zhengxin Wang Xuyong Wei Xiao Xu Arouse potential stemness: Intrinsic and acquired stem cell therapeutic strategies for advanced liver diseases Cell Insight Stem cell Intrinsic Acquired Advanced liver diseases Therapeutic strategy |
| title | Arouse potential stemness: Intrinsic and acquired stem cell therapeutic strategies for advanced liver diseases |
| title_full | Arouse potential stemness: Intrinsic and acquired stem cell therapeutic strategies for advanced liver diseases |
| title_fullStr | Arouse potential stemness: Intrinsic and acquired stem cell therapeutic strategies for advanced liver diseases |
| title_full_unstemmed | Arouse potential stemness: Intrinsic and acquired stem cell therapeutic strategies for advanced liver diseases |
| title_short | Arouse potential stemness: Intrinsic and acquired stem cell therapeutic strategies for advanced liver diseases |
| title_sort | arouse potential stemness intrinsic and acquired stem cell therapeutic strategies for advanced liver diseases |
| topic | Stem cell Intrinsic Acquired Advanced liver diseases Therapeutic strategy |
| url | http://www.sciencedirect.com/science/article/pii/S2772892723000391 |
| work_keys_str_mv | AT yisusong arousepotentialstemnessintrinsicandacquiredstemcelltherapeuticstrategiesforadvancedliverdiseases AT zhengyanglu arousepotentialstemnessintrinsicandacquiredstemcelltherapeuticstrategiesforadvancedliverdiseases AT wenzhishu arousepotentialstemnessintrinsicandacquiredstemcelltherapeuticstrategiesforadvancedliverdiseases AT zexiang arousepotentialstemnessintrinsicandacquiredstemcelltherapeuticstrategiesforadvancedliverdiseases AT zhengxinwang arousepotentialstemnessintrinsicandacquiredstemcelltherapeuticstrategiesforadvancedliverdiseases AT xuyongwei arousepotentialstemnessintrinsicandacquiredstemcelltherapeuticstrategiesforadvancedliverdiseases AT xiaoxu arousepotentialstemnessintrinsicandacquiredstemcelltherapeuticstrategiesforadvancedliverdiseases |