Up-regulation of microglial cathepsin C expression and activity in lipopolysaccharide-induced neuroinflammation

Up-regulation of microglial cathepsin C expression and activity in lipopolysaccharide-induced neuroinflammation

<p>Abstract</p> <p>Background</p> <p>Cathepsin C (Cat C) functions as a central coordinator for activation of many serine proteases in inflammatory cells. It has been recognized that Cat C is responsible for neutrophil recruitment and production of chemokines and cytoki...

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Bibliographic Details
Main Authors: Fan Kai, Wu Xuefei, Fan Bin, Li Ning, Lin Yongzhong, Yao Yiwen, Ma Jianmei
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Journal of Neuroinflammation
Subjects:
Cathepsin C
Microglia
Lipopolysaccharide
Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/9/1/96

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