Investigation the mechanism of iron overload-induced colonic inflammation following ferric citrate exposure

Investigation the mechanism of iron overload-induced colonic inflammation following ferric citrate exposure

Iron overload occurs due to excessive iron intake compared to the body’s demand, leading to iron deposition and impairment of multiple organ functions. Our previous study demonstrated that chronic oral administration of ferric citrate (FC) caused colonic inflammatory injury. However, the precise mec...

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Bibliographic Details
Main Authors: Yu Xia, Zhengli Chen, Chao Huang, Liangqin Shi, Wenjing Ma, Xiwen Chen, Yucong Liu, Yao Wang, Chunyu Cai, Yixiang Huang, Wentao Liu, Riyi Shi, Qihui Luo
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Ferric citrate
Iron overload
Colonic inflammation
Pathogenic bacteria
SW480 cells
NF-κB signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324003178

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