Diffusion Tensor Imaging Detects Acute Pathology-Specific Changes in the P301L Tauopathy Mouse Model Following Traumatic Brain Injury

Diffusion Tensor Imaging Detects Acute Pathology-Specific Changes in the P301L Tauopathy Mouse Model Following Traumatic Brain Injury

Traumatic brain injury (TBI) has been linked with tauopathy. However, imaging methods that can non-invasively detect tau-protein abnormalities following TBI need further investigation. This study aimed to investigate the potential of diffusion tensor imaging (DTI) to detect tauopathy following TBI i...

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Bibliographic Details
Main Authors: Neha Soni, Rodrigo Medeiros, Khawlah Alateeq, Xuan Vinh To, Fatima A. Nasrallah
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Neuroscience
Subjects:
traumatic brain injury
diffusion tensor imaging
transgenic
tau-hyperphosphorylation
astrocytes
microglia
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.611451/full

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