Systematic review on comparative outcomes in cell-based regeneration techniques vs. traditional techniques in osseointegration of implants in total knee arthroplasty
Background: Total Knee Arthroplasty (TKA), a proven and cost-effective orthopedic surgical technique, consistently reduces preoperative morbidity, enhances functional capacity, and alleviates pain in degenerative knee osteoarthritis.Objectives: The aim of this study was to compare cell-based and tra...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Kashan University of Medical Sciences
2023-12-01
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| Series: | Archives of Trauma Research |
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| Online Access: | https://archtrauma.kaums.ac.ir/article_184614_15d4d741de0e597092033fbb851d60b1.pdf |
| _version_ | 1797341408378486784 |
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| author | Rushikesh Ghongade Ganesh Pundkar Rajendra Baitule Sangram Deshmukh Sumit Tarekar Kishor Sonwane |
| author_facet | Rushikesh Ghongade Ganesh Pundkar Rajendra Baitule Sangram Deshmukh Sumit Tarekar Kishor Sonwane |
| author_sort | Rushikesh Ghongade |
| collection | DOAJ |
| description | Background: Total Knee Arthroplasty (TKA), a proven and cost-effective orthopedic surgical technique, consistently reduces preoperative morbidity, enhances functional capacity, and alleviates pain in degenerative knee osteoarthritis.Objectives: The aim of this study was to compare cell-based and traditional techniques in Osseointegration in Total Knee Arthroplasty.Methods: The literature search was conducted, across various electronic databases including Google Scholar, PubMed, Web of Science, Scopus, and the Cochrane Library. The search was conducted from 2001 to 2022, aiming to identify studies related to TKA and the various techniques employed in the procedure. Articles were screened based on the relevance to cell-based and traditional Osseointegration techniques, focusing on extracting information related to outcomes and complications.Results: We included 11 studies in the study, employing the Cochrane 'Risk of Bias tool' to assess bias in randomized trials across five domains. The majority of articles demonstrated low risk (56.36%), signifying reliability, while 'Unclear' studies (32.73%) had some ambiguity without invalidating results. Studies classified as 'High risk' (10.91%) indicated substantial bias and potential errors. Our findings suggest that cell-based techniques are efficient for the treatment of TKA.Conclusion: Osseointegration presents significant advantages in terms of function and pain relief for patients willing to accept associated risks. Cell-based techniques have proven effective in preventing the need for revision in TKA, demonstrating long-term effects. |
| first_indexed | 2024-03-08T10:18:39Z |
| format | Article |
| id | doaj.art-4fe0b135d02941beab6e6bcc77aaaecc |
| institution | Directory Open Access Journal |
| issn | 2251-953X 2251-9599 |
| language | English |
| last_indexed | 2024-03-08T10:18:39Z |
| publishDate | 2023-12-01 |
| publisher | Kashan University of Medical Sciences |
| record_format | Article |
| series | Archives of Trauma Research |
| spelling | doaj.art-4fe0b135d02941beab6e6bcc77aaaecc2024-01-28T08:59:14ZengKashan University of Medical SciencesArchives of Trauma Research2251-953X2251-95992023-12-0112417117810.48307/atr.2023.184614184614Systematic review on comparative outcomes in cell-based regeneration techniques vs. traditional techniques in osseointegration of implants in total knee arthroplastyRushikesh Ghongade0Ganesh Pundkar1Rajendra Baitule2Sangram Deshmukh3Sumit Tarekar4Kishor Sonwane5Department of Orthopaedics, Dr. Panjabrao Deshmukh Memorial Medical College and Hospital, Amravati, Maharashtra, IndiaDepartment of Orthopaedics, Dr. Panjabrao Deshmukh Memorial Medical College and Hospital, Amravati, Maharashtra, IndiaDepartment of Orthopaedics, Dr. Panjabrao Deshmukh Memorial Medical College and Hospital, Amravati, Maharashtra, IndiaDepartment of Orthopaedics, Dr. Panjabrao Deshmukh Memorial Medical College and Hospital, Amravati, Maharashtra, IndiaDepartment of Orthopaedics, Dr. Panjabrao Deshmukh Memorial Medical College and Hospital, Amravati, Maharashtra, IndiaDepartment of Orthopaedics, Dr. Panjabrao Deshmukh Memorial Medical College and Hospital, Amravati, Maharashtra, IndiaBackground: Total Knee Arthroplasty (TKA), a proven and cost-effective orthopedic surgical technique, consistently reduces preoperative morbidity, enhances functional capacity, and alleviates pain in degenerative knee osteoarthritis.Objectives: The aim of this study was to compare cell-based and traditional techniques in Osseointegration in Total Knee Arthroplasty.Methods: The literature search was conducted, across various electronic databases including Google Scholar, PubMed, Web of Science, Scopus, and the Cochrane Library. The search was conducted from 2001 to 2022, aiming to identify studies related to TKA and the various techniques employed in the procedure. Articles were screened based on the relevance to cell-based and traditional Osseointegration techniques, focusing on extracting information related to outcomes and complications.Results: We included 11 studies in the study, employing the Cochrane 'Risk of Bias tool' to assess bias in randomized trials across five domains. The majority of articles demonstrated low risk (56.36%), signifying reliability, while 'Unclear' studies (32.73%) had some ambiguity without invalidating results. Studies classified as 'High risk' (10.91%) indicated substantial bias and potential errors. Our findings suggest that cell-based techniques are efficient for the treatment of TKA.Conclusion: Osseointegration presents significant advantages in terms of function and pain relief for patients willing to accept associated risks. Cell-based techniques have proven effective in preventing the need for revision in TKA, demonstrating long-term effects.https://archtrauma.kaums.ac.ir/article_184614_15d4d741de0e597092033fbb851d60b1.pdfknee arthroplastyosseointegrationcell techniquesmetal implantsosteoarthritis |
| spellingShingle | Rushikesh Ghongade Ganesh Pundkar Rajendra Baitule Sangram Deshmukh Sumit Tarekar Kishor Sonwane Systematic review on comparative outcomes in cell-based regeneration techniques vs. traditional techniques in osseointegration of implants in total knee arthroplasty Archives of Trauma Research knee arthroplasty osseointegration cell techniques metal implants osteoarthritis |
| title | Systematic review on comparative outcomes in cell-based regeneration techniques vs. traditional techniques in osseointegration of implants in total knee arthroplasty |
| title_full | Systematic review on comparative outcomes in cell-based regeneration techniques vs. traditional techniques in osseointegration of implants in total knee arthroplasty |
| title_fullStr | Systematic review on comparative outcomes in cell-based regeneration techniques vs. traditional techniques in osseointegration of implants in total knee arthroplasty |
| title_full_unstemmed | Systematic review on comparative outcomes in cell-based regeneration techniques vs. traditional techniques in osseointegration of implants in total knee arthroplasty |
| title_short | Systematic review on comparative outcomes in cell-based regeneration techniques vs. traditional techniques in osseointegration of implants in total knee arthroplasty |
| title_sort | systematic review on comparative outcomes in cell based regeneration techniques vs traditional techniques in osseointegration of implants in total knee arthroplasty |
| topic | knee arthroplasty osseointegration cell techniques metal implants osteoarthritis |
| url | https://archtrauma.kaums.ac.ir/article_184614_15d4d741de0e597092033fbb851d60b1.pdf |
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