Effect of Ispaghula and Oxyphenonium Bromide on the Symptoms of Irritable Bowel Syndrome - A Comparative Study
Background: Irritable bowel syndrome is a chronic continuous or remittent gastrointestinal illness characterized by frequent unexplained symptoms that include abdominal pain, bloating, and bowel disturbance, in our country, no study has been conducted using the Ispaghula husk and oxyphenonium bromid...
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| Format: | Article |
| Language: | English |
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Bangabandhu Sheikh Mujib Medical University
2010-07-01
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| Series: | Bangabandhu Sheikh Mujib Medical University Journal |
| Subjects: | |
| Online Access: | https://www.banglajol.info/index.php/BSMMUJ/article/view/5506 |
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| author | B Paik SK Saha H Masud MA Kabir PK Roy M Hasan |
| author_facet | B Paik SK Saha H Masud MA Kabir PK Roy M Hasan |
| author_sort | B Paik |
| collection | DOAJ |
| description | Background: Irritable bowel syndrome is a chronic continuous or remittent gastrointestinal illness characterized by
frequent unexplained symptoms that include abdominal pain, bloating, and bowel disturbance, in our country, no study
has been conducted using the Ispaghula husk and oxyphenonium bromide for the treatment of IBS patients. Objectives:
To compare the efficacy of treatment with Ispaghula husk and Oxyphenonium bromide. Methods: Total sixty patients
diagnosed clinically as irritable bowel syndrome irrespective of subtype who fulfilled the Rome II criteria were included
equally into two groups-Group-I (Ispaghula group) & Group-II (Oxyphenonium group). In Group-I patients were given
30gm of Ispaghula husk at night daily and in Group-II patients were given 5mg of oxyphenonium bromide. After six
weeks the clinical parameters of both the groups recorded in the case record forms were taken for analysis. Results: The
mean age of the patients in the Group- I were 33.4±11.9 yrs and that of the patients in the Group-II were 31.0±17.5 yrs.
Male and female ratio in group I was 14:1 and in group II was 23:7. Most of the patients were recorded in the age group
of 26-30 in both groups. Symptom free patients were graded in 16.7% patients in Group-I and in 20% patients in Group-
II. No improvement was occurred in 16.7% patients in Group-I and in 10% patients in Group-II. Conclusions: Ispaghula
husk shows the better efficacy to improve the symptoms of IBS like abdominal pain or discomfort and sense of well being
than Oxyphenonium bromide. Oxephenonium bromide shows the better efficacy to decrease the stool frequency from
base line than Ispaghula husk.
DOI: 10.3329/bsmmuj.v3i1.5506
BSMMU J 2010; 3(1): 3-8 |
| first_indexed | 2024-12-11T02:29:00Z |
| format | Article |
| id | doaj.art-4fe48437b94d49e39375b3e8e60c9243 |
| institution | Directory Open Access Journal |
| issn | 2074-2908 2224-7750 |
| language | English |
| last_indexed | 2024-12-11T02:29:00Z |
| publishDate | 2010-07-01 |
| publisher | Bangabandhu Sheikh Mujib Medical University |
| record_format | Article |
| series | Bangabandhu Sheikh Mujib Medical University Journal |
| spelling | doaj.art-4fe48437b94d49e39375b3e8e60c92432022-12-22T01:23:51ZengBangabandhu Sheikh Mujib Medical UniversityBangabandhu Sheikh Mujib Medical University Journal2074-29082224-77502010-07-013110.3329/bsmmuj.v3i1.55064009Effect of Ispaghula and Oxyphenonium Bromide on the Symptoms of Irritable Bowel Syndrome - A Comparative StudyB Paik0SK Saha1H Masud2MA Kabir3PK Roy4M Hasan5Assistant Professor, Department of Gastroenterolgoy, Khulna Medical College, KhulnaAssociate Professor, Department of Gastroenterology, BSMMU, Shahbag, Dhaka.Associate Professor, Department of Gastroenterology, BSMMU, Shahbag, Dhaka.Associate Professor, Department of Gastroenterology, BSMMU, Shahbag, Dhaka.Professor, Department of Gastroenterology, BSMMU, Shahbag, Dhaka.Professor, Department of Gastroenterology, BSMMU, Shahbag, Dhaka.Background: Irritable bowel syndrome is a chronic continuous or remittent gastrointestinal illness characterized by frequent unexplained symptoms that include abdominal pain, bloating, and bowel disturbance, in our country, no study has been conducted using the Ispaghula husk and oxyphenonium bromide for the treatment of IBS patients. Objectives: To compare the efficacy of treatment with Ispaghula husk and Oxyphenonium bromide. Methods: Total sixty patients diagnosed clinically as irritable bowel syndrome irrespective of subtype who fulfilled the Rome II criteria were included equally into two groups-Group-I (Ispaghula group) & Group-II (Oxyphenonium group). In Group-I patients were given 30gm of Ispaghula husk at night daily and in Group-II patients were given 5mg of oxyphenonium bromide. After six weeks the clinical parameters of both the groups recorded in the case record forms were taken for analysis. Results: The mean age of the patients in the Group- I were 33.4±11.9 yrs and that of the patients in the Group-II were 31.0±17.5 yrs. Male and female ratio in group I was 14:1 and in group II was 23:7. Most of the patients were recorded in the age group of 26-30 in both groups. Symptom free patients were graded in 16.7% patients in Group-I and in 20% patients in Group- II. No improvement was occurred in 16.7% patients in Group-I and in 10% patients in Group-II. Conclusions: Ispaghula husk shows the better efficacy to improve the symptoms of IBS like abdominal pain or discomfort and sense of well being than Oxyphenonium bromide. Oxephenonium bromide shows the better efficacy to decrease the stool frequency from base line than Ispaghula husk. DOI: 10.3329/bsmmuj.v3i1.5506 BSMMU J 2010; 3(1): 3-8https://www.banglajol.info/index.php/BSMMUJ/article/view/5506irritable bowl syndrome |
| spellingShingle | B Paik SK Saha H Masud MA Kabir PK Roy M Hasan Effect of Ispaghula and Oxyphenonium Bromide on the Symptoms of Irritable Bowel Syndrome - A Comparative Study Bangabandhu Sheikh Mujib Medical University Journal irritable bowl syndrome |
| title | Effect of Ispaghula and Oxyphenonium Bromide on the Symptoms of Irritable Bowel Syndrome - A Comparative Study |
| title_full | Effect of Ispaghula and Oxyphenonium Bromide on the Symptoms of Irritable Bowel Syndrome - A Comparative Study |
| title_fullStr | Effect of Ispaghula and Oxyphenonium Bromide on the Symptoms of Irritable Bowel Syndrome - A Comparative Study |
| title_full_unstemmed | Effect of Ispaghula and Oxyphenonium Bromide on the Symptoms of Irritable Bowel Syndrome - A Comparative Study |
| title_short | Effect of Ispaghula and Oxyphenonium Bromide on the Symptoms of Irritable Bowel Syndrome - A Comparative Study |
| title_sort | effect of ispaghula and oxyphenonium bromide on the symptoms of irritable bowel syndrome a comparative study |
| topic | irritable bowl syndrome |
| url | https://www.banglajol.info/index.php/BSMMUJ/article/view/5506 |
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