Summary: | Abstract. Acinetobacter baumannii is a frequent cause of nosocomial infections. Here we report an intermittent outbreak caused by the emerging carbapenem-resistant A. baumannii (CRAB) clone ST457 and assess the effectiveness of patient screening for outbreak control. CRAB isolates were collected from 74 patients admitted to the respiratory intensive care unit of a tertiary hospital between May 2018 and March 2019. Fourteen CRAB isolates were assigned to ST457, and 13 belonged to an outbreak clone, as determined by phylogenomic analysis. Strict patient screening was started at the respiratory intensive care unit on May 2019, through which a ST457-positive patient transferred from the intensive care unit was detected. No positive patients were detected within 3 months onwards. The results of this study highlight the importance of rigorous infection prevention and control measures, combined with patient screening, in controlling the CRAB outbreak.
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