An NTS-CeA projection modulates depression-like behaviors in a mouse model of chronic pain

An NTS-CeA projection modulates depression-like behaviors in a mouse model of chronic pain

Depressive symptoms comorbid with chronic pain are a common health problem, but the underlying neural circuit mechanisms remain elusive. Here, we identify a glutamatergic projection from the nucleus of the solitary tract (NTS) to the central nucleus of the amygdala (CeA) that mediates depression-lik...

Full description

Bibliographic Details
Main Authors: Shilang He, Xuelin Huang, Jun Zheng, Yuehong Zhang, Xiangcai Ruan
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Neurobiology of Disease
Subjects:
Depression
Chronic pain
Solitary tract
Amygdala
Neural pathways
Optogenetics
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996122002856

Similar Items

Similar Items