Non-coding RNAs and gastrointestinal cancers prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies
AimProvide an overview and a systematic evaluation of the evidence quality on the association between non-coding RNAs (ncRNAs) and prognosis value for gastrointestinal cancers (GICs).MethodsWe searched the literature from three electronic databases: Pubmed, Embase, and Web of science, then carefully...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-07-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2023.1193665/full |
| _version_ | 1797776304262610944 |
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| author | Bowen Zha Yuxi Luo Muladili Kamili Xiaqin Zha |
| author_facet | Bowen Zha Yuxi Luo Muladili Kamili Xiaqin Zha |
| author_sort | Bowen Zha |
| collection | DOAJ |
| description | AimProvide an overview and a systematic evaluation of the evidence quality on the association between non-coding RNAs (ncRNAs) and prognosis value for gastrointestinal cancers (GICs).MethodsWe searched the literature from three electronic databases: Pubmed, Embase, and Web of science, then carefully screened and extracted the primary information and results from the included articles. We use A measurable systematic review and meta-analysis evaluation tool (AMSTAR2) to evaluate the quality of methodology and then use the Grading of Recommendations Assessment 2, Development and Evaluation guideline (GRADE) make sure the reliability of the meta-analysis.ResultsOverall, 182 meta-analyses from 58 studies were included in this study. Most of these studies are of low or very low quality. Using the scoring tool, we found that only two meta-analyses were rated as high reliability, and 17 meta-analyses were rated as medium reliability.ConclusionsAlthough ncRNA has good prognostic value in some studies, only a tiny amount of evidence is highly credible at present. More research is needed in the future.PROSPERO registration numberCRD42022382296. |
| first_indexed | 2024-03-12T22:48:06Z |
| format | Article |
| id | doaj.art-4fe75c6586094fb6b3aa758921bbaedd |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-03-12T22:48:06Z |
| publishDate | 2023-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-4fe75c6586094fb6b3aa758921bbaedd2023-07-20T20:16:15ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-07-011310.3389/fonc.2023.11936651193665Non-coding RNAs and gastrointestinal cancers prognosis: an umbrella review of systematic reviews and meta-analyses of observational studiesBowen Zha0Yuxi Luo1Muladili Kamili2Xiaqin Zha3The Sixth Clinical Medical College, Capital Medical University, Beijing, ChinaThe First Clinical Medical College, Capital Medical University, Beijing, ChinaThe Sixth Clinical Medical College, Capital Medical University, Beijing, ChinaDepartment of Blood Purification, University Affiliated Second Hospital, Nanchang, ChinaAimProvide an overview and a systematic evaluation of the evidence quality on the association between non-coding RNAs (ncRNAs) and prognosis value for gastrointestinal cancers (GICs).MethodsWe searched the literature from three electronic databases: Pubmed, Embase, and Web of science, then carefully screened and extracted the primary information and results from the included articles. We use A measurable systematic review and meta-analysis evaluation tool (AMSTAR2) to evaluate the quality of methodology and then use the Grading of Recommendations Assessment 2, Development and Evaluation guideline (GRADE) make sure the reliability of the meta-analysis.ResultsOverall, 182 meta-analyses from 58 studies were included in this study. Most of these studies are of low or very low quality. Using the scoring tool, we found that only two meta-analyses were rated as high reliability, and 17 meta-analyses were rated as medium reliability.ConclusionsAlthough ncRNA has good prognostic value in some studies, only a tiny amount of evidence is highly credible at present. More research is needed in the future.PROSPERO registration numberCRD42022382296.https://www.frontiersin.org/articles/10.3389/fonc.2023.1193665/fullncRNAgastrointestinal cancersprognosisumbrella reviewmiRNA |
| spellingShingle | Bowen Zha Yuxi Luo Muladili Kamili Xiaqin Zha Non-coding RNAs and gastrointestinal cancers prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies Frontiers in Oncology ncRNA gastrointestinal cancers prognosis umbrella review miRNA |
| title | Non-coding RNAs and gastrointestinal cancers prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies |
| title_full | Non-coding RNAs and gastrointestinal cancers prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies |
| title_fullStr | Non-coding RNAs and gastrointestinal cancers prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies |
| title_full_unstemmed | Non-coding RNAs and gastrointestinal cancers prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies |
| title_short | Non-coding RNAs and gastrointestinal cancers prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies |
| title_sort | non coding rnas and gastrointestinal cancers prognosis an umbrella review of systematic reviews and meta analyses of observational studies |
| topic | ncRNA gastrointestinal cancers prognosis umbrella review miRNA |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2023.1193665/full |
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