Ocular Manifestations in Patients with Psoriasis
Background and purpose: Psoriasis is a systemically pathogenic immune-mediated, chronic inflammatory disease that mostly affects the skin. Ocular diseases, which are frequently nonspecific or just slightly bothersome in psoriasis, are not well-known. This study investigated ocular manifestations in...
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| Format: | Article |
| Language: | English |
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Mazandaran University of Medical Sciences
2023-09-01
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| Series: | Journal of Mazandaran University of Medical Sciences |
| Subjects: | |
| Online Access: | http://jmums.mazums.ac.ir/article-1-18798-en.pdf |
| _version_ | 1797542597328109568 |
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| author | Haniyeh Ghasrsaz Reza Jafari Zohreh Haj Heydari Ghasem Rahmatpour Rokni |
| author_facet | Haniyeh Ghasrsaz Reza Jafari Zohreh Haj Heydari Ghasem Rahmatpour Rokni |
| author_sort | Haniyeh Ghasrsaz |
| collection | DOAJ |
| description | Background and purpose: Psoriasis is a systemically pathogenic immune-mediated, chronic inflammatory disease that mostly affects the skin. Ocular diseases, which are frequently nonspecific or just slightly bothersome in psoriasis, are not well-known. This study investigated ocular manifestations in patients with psoriasis.
Materials and methods: This cross-sectional study was conducted at Bu-Ali Sina hospital in Sari, Iran. Seventy-five patients with psoriasis matched by age and sex with 75 non-psoriatic controls were examined. Dermatology life quality index (DLQI) and psoriasis area and severity index (PASI) scores were calculated for every patient with psoriasis. Ocular surface disease index (OSDI) was measured in both groups. We did a slit-lamp examination, Schirmer I test, tear breakup time (TBUT) and fundoscopy in both groups.
Results: The mean age of patients was 40.11±13.88 years. The most common findings on our examinations were conjunctival hyperemia (38%), blepharitis (36%), MGD (33%), and pinguecula (26%). MGD and low TBUT were more common in patients with higher PASI and DLQI scores. OSDI score was also higher in patients with psoriasis.
Conclusion: Ocular surface conditions such as dry eye were more common among the participants and were correlated with duration and severity of the disease. Therefore, psoriasis patients should get frequent and routine eye exams to detect ocular disorders quicly and avoid their unintended effects. |
| first_indexed | 2024-03-10T13:32:49Z |
| format | Article |
| id | doaj.art-4febcba7717c49e787ce8d7fd4432c21 |
| institution | Directory Open Access Journal |
| issn | 1735-9260 1735-9279 |
| language | English |
| last_indexed | 2024-03-10T13:32:49Z |
| publishDate | 2023-09-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Mazandaran University of Medical Sciences |
| spelling | doaj.art-4febcba7717c49e787ce8d7fd4432c212023-11-21T07:44:40ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792023-09-01332247789Ocular Manifestations in Patients with PsoriasisHaniyeh Ghasrsaz0Reza Jafari1Zohreh Haj Heydari2Ghasem Rahmatpour Rokni3 Medical Student, Bu-Ali Educational, Research and Therapeutic Hospital, Mazandaran University of Medical Sciences, Sari, Iran Assistant Professor, Department of Ophthalmology, Bu-Ali Educational, Research and Therapeutic Hospital, Mazandaran University of Medical Sciences, Sari, Iran Professor, Department of Dermatology, Bu-Ali Educational, Research and Therapeutic Hospital, Mazandaran University of Medical Sciences, Sari, Iran Associate Professor, Department of Dermatology, Bu-Ali Educational, Research and Therapeutic Hospital, Mazandaran University of Medical Sciences, Sari, Iran Background and purpose: Psoriasis is a systemically pathogenic immune-mediated, chronic inflammatory disease that mostly affects the skin. Ocular diseases, which are frequently nonspecific or just slightly bothersome in psoriasis, are not well-known. This study investigated ocular manifestations in patients with psoriasis. Materials and methods: This cross-sectional study was conducted at Bu-Ali Sina hospital in Sari, Iran. Seventy-five patients with psoriasis matched by age and sex with 75 non-psoriatic controls were examined. Dermatology life quality index (DLQI) and psoriasis area and severity index (PASI) scores were calculated for every patient with psoriasis. Ocular surface disease index (OSDI) was measured in both groups. We did a slit-lamp examination, Schirmer I test, tear breakup time (TBUT) and fundoscopy in both groups. Results: The mean age of patients was 40.11±13.88 years. The most common findings on our examinations were conjunctival hyperemia (38%), blepharitis (36%), MGD (33%), and pinguecula (26%). MGD and low TBUT were more common in patients with higher PASI and DLQI scores. OSDI score was also higher in patients with psoriasis. Conclusion: Ocular surface conditions such as dry eye were more common among the participants and were correlated with duration and severity of the disease. Therefore, psoriasis patients should get frequent and routine eye exams to detect ocular disorders quicly and avoid their unintended effects.http://jmums.mazums.ac.ir/article-1-18798-en.pdfpsoriasiseyedry eyeocular psoriasismgd |
| spellingShingle | Haniyeh Ghasrsaz Reza Jafari Zohreh Haj Heydari Ghasem Rahmatpour Rokni Ocular Manifestations in Patients with Psoriasis Journal of Mazandaran University of Medical Sciences psoriasis eye dry eye ocular psoriasis mgd |
| title | Ocular Manifestations in Patients with Psoriasis |
| title_full | Ocular Manifestations in Patients with Psoriasis |
| title_fullStr | Ocular Manifestations in Patients with Psoriasis |
| title_full_unstemmed | Ocular Manifestations in Patients with Psoriasis |
| title_short | Ocular Manifestations in Patients with Psoriasis |
| title_sort | ocular manifestations in patients with psoriasis |
| topic | psoriasis eye dry eye ocular psoriasis mgd |
| url | http://jmums.mazums.ac.ir/article-1-18798-en.pdf |
| work_keys_str_mv | AT haniyehghasrsaz ocularmanifestationsinpatientswithpsoriasis AT rezajafari ocularmanifestationsinpatientswithpsoriasis AT zohrehhajheydari ocularmanifestationsinpatientswithpsoriasis AT ghasemrahmatpourrokni ocularmanifestationsinpatientswithpsoriasis |