Nutrients Interaction with the Immune System
This study described the interactions of different nutritional components with the immune system. A detailed search was carried out on Google Scholar and PubMed databases to find out the relevant research studies using different keywords, such as "Nutrients", "Micronutrients", an...
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| Format: | Article |
| Language: | English |
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Razi Vaccine and Serum Research Institute
2021-12-01
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| Series: | Archives of Razi Institute |
| Subjects: | |
| Online Access: | https://archrazi.areeo.ac.ir/article_125099_318c1998272c0f707c1a5d477c549da3.pdf |
| _version_ | 1818523581260234752 |
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| author | S Noor S Piscopo A Gasmi |
| author_facet | S Noor S Piscopo A Gasmi |
| author_sort | S Noor |
| collection | DOAJ |
| description | This study described the interactions of different nutritional components with the immune system. A detailed search was carried out on Google Scholar and PubMed databases to find out the relevant research studies using different keywords, such as "Nutrients", "Micronutrients", and "Immune system and micronutrients". Only those papers that discussed the interactions between nutrients and the components of the immune system were included in the study. This research outlined the impact of different vitamins, trace elements or metals, amino acids, and fatty acids on different immune system components. It was found that vitamins, such as vitamin A, D, and C, tend to help immune cell differentiation and enhance the expression of different cytokines. Vitamins also contribute to the proliferation of T and B cells and impact the production of white blood cells. Similarly, trace elements or metals act as enzyme cofactors and control different immune response cycles by controlling the expression of cytokines, chemokines, and other signaling molecules. Moreover, different essential and non-essential amino acids play important roles in immune system development as they are primarily involved in protein synthesis. Amino acids, such as arginine, glutamine, and alanine, modulate the expression of cytokines and also control the migration and transmigration capabilities of macrophages. They also enhance the phagocytic properties of macrophages and neutrophils. In a similar way, fatty acids act as anti-inflammatory agents since they can decrease the expression of major histocompatibility complex class I (MHC-I) and MHC-II. Furthermore, they inhibit the secretion of different inflammatory cytokines. In conclusion, all the components of our daily diet are associated with the development of the immune system, and understanding their interactions is important for future immune therapies and drug development. |
| first_indexed | 2024-12-11T05:46:38Z |
| format | Article |
| id | doaj.art-4feeac4d9ae742b08164c19fd253f750 |
| institution | Directory Open Access Journal |
| issn | 0365-3439 2008-9872 |
| language | English |
| last_indexed | 2024-12-11T05:46:38Z |
| publishDate | 2021-12-01 |
| publisher | Razi Vaccine and Serum Research Institute |
| record_format | Article |
| series | Archives of Razi Institute |
| spelling | doaj.art-4feeac4d9ae742b08164c19fd253f7502022-12-22T01:18:56ZengRazi Vaccine and Serum Research InstituteArchives of Razi Institute0365-34392008-98722021-12-017661579158810.22092/ari.2021.356098.1775125099Nutrients Interaction with the Immune SystemS Noor0S Piscopo1A Gasmi2Institute of Molecular Biology and Biotechnology, Bahauddin Zakariya University Multan, PakistanResearch and Development Department, Nutri-Logics SA, Weiswampach, LuxembourgSociété Francophone de Nutrithérapie et de Nutrigénétique Appliquée, Villeurbanne, FranceThis study described the interactions of different nutritional components with the immune system. A detailed search was carried out on Google Scholar and PubMed databases to find out the relevant research studies using different keywords, such as "Nutrients", "Micronutrients", and "Immune system and micronutrients". Only those papers that discussed the interactions between nutrients and the components of the immune system were included in the study. This research outlined the impact of different vitamins, trace elements or metals, amino acids, and fatty acids on different immune system components. It was found that vitamins, such as vitamin A, D, and C, tend to help immune cell differentiation and enhance the expression of different cytokines. Vitamins also contribute to the proliferation of T and B cells and impact the production of white blood cells. Similarly, trace elements or metals act as enzyme cofactors and control different immune response cycles by controlling the expression of cytokines, chemokines, and other signaling molecules. Moreover, different essential and non-essential amino acids play important roles in immune system development as they are primarily involved in protein synthesis. Amino acids, such as arginine, glutamine, and alanine, modulate the expression of cytokines and also control the migration and transmigration capabilities of macrophages. They also enhance the phagocytic properties of macrophages and neutrophils. In a similar way, fatty acids act as anti-inflammatory agents since they can decrease the expression of major histocompatibility complex class I (MHC-I) and MHC-II. Furthermore, they inhibit the secretion of different inflammatory cytokines. In conclusion, all the components of our daily diet are associated with the development of the immune system, and understanding their interactions is important for future immune therapies and drug development.https://archrazi.areeo.ac.ir/article_125099_318c1998272c0f707c1a5d477c549da3.pdfnutrientsimmune systemvitaminst cellsb cells |
| spellingShingle | S Noor S Piscopo A Gasmi Nutrients Interaction with the Immune System Archives of Razi Institute nutrients immune system vitamins t cells b cells |
| title | Nutrients Interaction with the Immune System |
| title_full | Nutrients Interaction with the Immune System |
| title_fullStr | Nutrients Interaction with the Immune System |
| title_full_unstemmed | Nutrients Interaction with the Immune System |
| title_short | Nutrients Interaction with the Immune System |
| title_sort | nutrients interaction with the immune system |
| topic | nutrients immune system vitamins t cells b cells |
| url | https://archrazi.areeo.ac.ir/article_125099_318c1998272c0f707c1a5d477c549da3.pdf |
| work_keys_str_mv | AT snoor nutrientsinteractionwiththeimmunesystem AT spiscopo nutrientsinteractionwiththeimmunesystem AT agasmi nutrientsinteractionwiththeimmunesystem |