Clinicopathological significance and prognostic role of LAG3 + tumor-infiltrating lymphocytes in colorectal cancer; relationship with sidedness

Clinicopathological significance and prognostic role of LAG3 + tumor-infiltrating lymphocytes in colorectal cancer; relationship with sidedness

Abstract Background It is well-documented that the interplay between tumor-infiltrating lymphocytes (TILs) and tumor cells is a major determining factor in cancer progression. CD45RO seems to be a reliable indicator for predicting prognosis and disease outcome, along with CD3 and CD8 markers. LAG-3...

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Bibliographic Details
Main Authors: Shirin Tavana, Zahra Mokhtari, Mohammad Hossein Sanei, Zahra Heidari, Amir-Reza Dehghanian, Zahra Faghih, Marzieh Rezaei
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Cancer Cell International
Subjects:
Colorectal cancer
Immunohistochemistry
Prognostic marker
Tumor microenvironment
LAG3
CD45RO
Online Access:https://doi.org/10.1186/s12935-023-02864-3

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