Infiltrative Type I Collagen in the Treatment of Morton’s Neuroma: A Mini-Series
Morton’s neuroma (MN) is a compressive neuropathy of the common plantar digital nerve, most commonly affecting the third inter-digital space. The conservative approach is the first recommended treatment option. However, other different approaches have been proposed, offering several options of treat...
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| Format: | Article |
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MDPI AG
2023-07-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/14/4640 |
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| author | Federico Giarda Adele Agostini Stefano Colonna Luciana Sciumè Alberto Meroni Giovanna Beretta Davide Dalla Costa |
| author_facet | Federico Giarda Adele Agostini Stefano Colonna Luciana Sciumè Alberto Meroni Giovanna Beretta Davide Dalla Costa |
| author_sort | Federico Giarda |
| collection | DOAJ |
| description | Morton’s neuroma (MN) is a compressive neuropathy of the common plantar digital nerve, most commonly affecting the third inter-digital space. The conservative approach is the first recommended treatment option. However, other different approaches have been proposed, offering several options of treatments, where, several degrees of efficacy and safety have been reported. We treated five consecutive patients affected by MN through three indirect ultrasound-guided injections of type I porcine collagen at weekly intervals. All patients were assessed before the treatment, after the treatment and up to 6 months after the last injection via AOFAS and VNS scores for pain, in which the function and pain were evaluated, respectively. In all patients, both analyzed variables progressively ameliorated, with benefits lasting until the last follow-up. The trend of the scores during the follow-up showed significant statistical differences. No side effects occurred. To our knowledge, this is the first study on injections of type I porcine collagen for the treatment of Morton’s neuroma. Future research is needed to confirm the positive trend achieved in this MN mini-series. |
| first_indexed | 2024-03-11T00:57:38Z |
| format | Article |
| id | doaj.art-4ff22541447b419a94929b30488659d2 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T00:57:38Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-4ff22541447b419a94929b30488659d22023-11-18T19:51:47ZengMDPI AGJournal of Clinical Medicine2077-03832023-07-011214464010.3390/jcm12144640Infiltrative Type I Collagen in the Treatment of Morton’s Neuroma: A Mini-SeriesFederico Giarda0Adele Agostini1Stefano Colonna2Luciana Sciumè3Alberto Meroni4Giovanna Beretta5Davide Dalla Costa6Unit of Rehabilitation Medicine and Neurorehabilitation, Department of Neuroscience, ASST Niguarda Hospital, 20162 Milan, ItalyDepartment of Biomedical Sciences for Health, Università degli Studi di Milano, 20133 Milan, ItalyUnit of Rehabilitation Medicine and Neurorehabilitation, Department of Neuroscience, ASST Niguarda Hospital, 20162 Milan, ItalyUnit of Rehabilitation Medicine and Neurorehabilitation, Department of Neuroscience, ASST Niguarda Hospital, 20162 Milan, ItalyDepartment of Orthopedic Surgery and Traumatology, ASST Niguarda Hospital, 20162 Milan, ItalyUnit of Rehabilitation Medicine and Neurorehabilitation, Department of Neuroscience, ASST Niguarda Hospital, 20162 Milan, ItalyUnit of Rehabilitation Medicine and Neurorehabilitation, Department of Neuroscience, ASST Niguarda Hospital, 20162 Milan, ItalyMorton’s neuroma (MN) is a compressive neuropathy of the common plantar digital nerve, most commonly affecting the third inter-digital space. The conservative approach is the first recommended treatment option. However, other different approaches have been proposed, offering several options of treatments, where, several degrees of efficacy and safety have been reported. We treated five consecutive patients affected by MN through three indirect ultrasound-guided injections of type I porcine collagen at weekly intervals. All patients were assessed before the treatment, after the treatment and up to 6 months after the last injection via AOFAS and VNS scores for pain, in which the function and pain were evaluated, respectively. In all patients, both analyzed variables progressively ameliorated, with benefits lasting until the last follow-up. The trend of the scores during the follow-up showed significant statistical differences. No side effects occurred. To our knowledge, this is the first study on injections of type I porcine collagen for the treatment of Morton’s neuroma. Future research is needed to confirm the positive trend achieved in this MN mini-series.https://www.mdpi.com/2077-0383/12/14/4640Morton’s neuromatype I porcine collagenclinical treatmentUS-guided injectioncase mini-series |
| spellingShingle | Federico Giarda Adele Agostini Stefano Colonna Luciana Sciumè Alberto Meroni Giovanna Beretta Davide Dalla Costa Infiltrative Type I Collagen in the Treatment of Morton’s Neuroma: A Mini-Series Journal of Clinical Medicine Morton’s neuroma type I porcine collagen clinical treatment US-guided injection case mini-series |
| title | Infiltrative Type I Collagen in the Treatment of Morton’s Neuroma: A Mini-Series |
| title_full | Infiltrative Type I Collagen in the Treatment of Morton’s Neuroma: A Mini-Series |
| title_fullStr | Infiltrative Type I Collagen in the Treatment of Morton’s Neuroma: A Mini-Series |
| title_full_unstemmed | Infiltrative Type I Collagen in the Treatment of Morton’s Neuroma: A Mini-Series |
| title_short | Infiltrative Type I Collagen in the Treatment of Morton’s Neuroma: A Mini-Series |
| title_sort | infiltrative type i collagen in the treatment of morton s neuroma a mini series |
| topic | Morton’s neuroma type I porcine collagen clinical treatment US-guided injection case mini-series |
| url | https://www.mdpi.com/2077-0383/12/14/4640 |
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