Clinical features and treatment outcomes of Vibrio vulnificus infection in the coastal city of Ningbo, China
BackgroundVibrio vulnificus is a gram-negative, opportunistic pathogen common to warm waters worldwide. Human V. vulnificus infection is rare and typically affects those residing in coastal areas during the summer months, but it causes rapid deterioration and is fatal.MethodsThe medical records of s...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-07-01
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| Series: | Frontiers in Microbiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2023.1220526/full |
| _version_ | 1797787956495253504 |
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| author | Jieyi Wang Xingbei Weng Yuesong Weng Quanjun Xu Yao Lu Yijun Mo |
| author_facet | Jieyi Wang Xingbei Weng Yuesong Weng Quanjun Xu Yao Lu Yijun Mo |
| author_sort | Jieyi Wang |
| collection | DOAJ |
| description | BackgroundVibrio vulnificus is a gram-negative, opportunistic pathogen common to warm waters worldwide. Human V. vulnificus infection is rare and typically affects those residing in coastal areas during the summer months, but it causes rapid deterioration and is fatal.MethodsThe medical records of six patients with sepsis caused by V. vulnificus infection who were treated at the First Affiliated Hospital of Ningbo University from 2020 to 2022 were retrospectively reviewed. The patient demographics, clinical symptoms, laboratory test results, treatments, and outcomes are summarized.ResultsVibrio vulnificus infection was confirmed by blood or pus culture, 16S ribosomal DNA sequencing, and metagenomic next-generation sequencing. All six patients were male with pre-existing liver diseases and two reported consuming seafood before the onset of symptoms. Of the six patients, four succumbed to the disease, two recovered, and one underwent leg amputation.ConclusionVibrio vulnificus infection progresses rapidly and is highly fatal, thus prompt and aggressive treatment is necessary. Vibrio vulnificus infection should be considered in older (>40 years) patients with a history of liver disease and recent consumption of seafood or exposure to seawater, especially those residing in coastal areas during the summer months. |
| first_indexed | 2024-03-13T01:29:00Z |
| format | Article |
| id | doaj.art-4ff550fbdd254d0f9096815414025355 |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-03-13T01:29:00Z |
| publishDate | 2023-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-4ff550fbdd254d0f90968154140253552023-07-04T09:24:58ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2023-07-011410.3389/fmicb.2023.12205261220526Clinical features and treatment outcomes of Vibrio vulnificus infection in the coastal city of Ningbo, ChinaJieyi WangXingbei WengYuesong WengQuanjun XuYao LuYijun MoBackgroundVibrio vulnificus is a gram-negative, opportunistic pathogen common to warm waters worldwide. Human V. vulnificus infection is rare and typically affects those residing in coastal areas during the summer months, but it causes rapid deterioration and is fatal.MethodsThe medical records of six patients with sepsis caused by V. vulnificus infection who were treated at the First Affiliated Hospital of Ningbo University from 2020 to 2022 were retrospectively reviewed. The patient demographics, clinical symptoms, laboratory test results, treatments, and outcomes are summarized.ResultsVibrio vulnificus infection was confirmed by blood or pus culture, 16S ribosomal DNA sequencing, and metagenomic next-generation sequencing. All six patients were male with pre-existing liver diseases and two reported consuming seafood before the onset of symptoms. Of the six patients, four succumbed to the disease, two recovered, and one underwent leg amputation.ConclusionVibrio vulnificus infection progresses rapidly and is highly fatal, thus prompt and aggressive treatment is necessary. Vibrio vulnificus infection should be considered in older (>40 years) patients with a history of liver disease and recent consumption of seafood or exposure to seawater, especially those residing in coastal areas during the summer months.https://www.frontiersin.org/articles/10.3389/fmicb.2023.1220526/fullVibrio vulnificussepsisseptic shockclinical featureslaboratory test |
| spellingShingle | Jieyi Wang Xingbei Weng Yuesong Weng Quanjun Xu Yao Lu Yijun Mo Clinical features and treatment outcomes of Vibrio vulnificus infection in the coastal city of Ningbo, China Frontiers in Microbiology Vibrio vulnificus sepsis septic shock clinical features laboratory test |
| title | Clinical features and treatment outcomes of Vibrio vulnificus infection in the coastal city of Ningbo, China |
| title_full | Clinical features and treatment outcomes of Vibrio vulnificus infection in the coastal city of Ningbo, China |
| title_fullStr | Clinical features and treatment outcomes of Vibrio vulnificus infection in the coastal city of Ningbo, China |
| title_full_unstemmed | Clinical features and treatment outcomes of Vibrio vulnificus infection in the coastal city of Ningbo, China |
| title_short | Clinical features and treatment outcomes of Vibrio vulnificus infection in the coastal city of Ningbo, China |
| title_sort | clinical features and treatment outcomes of vibrio vulnificus infection in the coastal city of ningbo china |
| topic | Vibrio vulnificus sepsis septic shock clinical features laboratory test |
| url | https://www.frontiersin.org/articles/10.3389/fmicb.2023.1220526/full |
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