ExlA Pore-Forming Toxin: Localization at the Bacterial Membrane, Regulation of Secretion by Cyclic-Di-GMP, and Detection In Vivo

ExlA Pore-Forming Toxin: Localization at the Bacterial Membrane, Regulation of Secretion by Cyclic-Di-GMP, and Detection In Vivo

ExlA is a highly virulent pore-forming toxin that has been recently discovered in outlier strains from <i>Pseudomonas aeruginosa</i>. ExlA is part of a two-partner secretion system, in which ExlA is the secreted passenger protein and ExlB the transporter embedded in the bacterial outer m...

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Bibliographic Details
Main Authors: Vincent Deruelle, Alice Berry, Stéphanie Bouillot, Viviana Job, Antoine P. Maillard, Sylvie Elsen, Philippe Huber
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Toxins
Subjects:
bacterial pore-forming toxin
two-partner secretion
c-di-GMP
<i>Pseudomonas aeruginosa</i>
toxin dosage
Online Access:https://www.mdpi.com/2072-6651/13/9/645

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