Verification EVestG recordings are vestibuloacoustic signals
Abstract Introduction Neural dysfunction is associated with aberrant nerve firing; thus, electrodiagnosis has the potential for objective diagnosis and quantification of neural dysfunction. Electrical stimulation alters nerve firing and may also have treatment potential. This article outlines some f...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-08-01
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| Series: | Laryngoscope Investigative Otolaryngology |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/lio2.862 |
| _version_ | 1798042184858992640 |
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| author | Brian Blakley Mehrangiz Ashiri Zahra Moussavi Brian Lithgow |
| author_facet | Brian Blakley Mehrangiz Ashiri Zahra Moussavi Brian Lithgow |
| author_sort | Brian Blakley |
| collection | DOAJ |
| description | Abstract Introduction Neural dysfunction is associated with aberrant nerve firing; thus, electrodiagnosis has the potential for objective diagnosis and quantification of neural dysfunction. Electrical stimulation alters nerve firing and may also have treatment potential. This article outlines some findings related to electrodiagnosis and electrical stimulation of the ear. The quasi‐synchronous firing of many vestibuloacoustic nerve fibers can produce an extracellular potential defined as a field potential (FP). Electrovestibulography (EVestG) is a method to record vestibuloacoustic signals and detect the associated FPs. A clear picture of the muscle‐, EEG‐, saccade‐related, or other artefactual origins, and the physiologic basis of FPs recorded with EVestG, is evolving. EVestG was applied to demonstrate the effect of electrical stimulation on spontaneous FPs in the ear canal. Methods Bilateral EVestG recordings were conducted on 14 guinea pigs before and after stimulation with 3–0.5 mA ipsilateral anodal electrical pulses before and after ablation via unilateral Scarpa's ganglionectomy to elucidate the origin of the EVestG recorded spontaneous FPs. Results Anodal electrical stimulation suppresses the recorded activity. There was a significant reduction of the level of recorded signal observed following anodal stimulation on the ablated but not the intact side. Conclusion Electrical stimulation of the external auditory canal reduces spontaneous electrical activity in the ear canal, some of which is due to central nervous system activity. The EVestG recorded FPs have a major vestibuloacoustic component. |
| first_indexed | 2024-04-11T22:31:57Z |
| format | Article |
| id | doaj.art-4ffa06c316c24b7fbd9e504335872a93 |
| institution | Directory Open Access Journal |
| issn | 2378-8038 |
| language | English |
| last_indexed | 2024-04-11T22:31:57Z |
| publishDate | 2022-08-01 |
| publisher | Wiley |
| record_format | Article |
| series | Laryngoscope Investigative Otolaryngology |
| spelling | doaj.art-4ffa06c316c24b7fbd9e504335872a932022-12-22T03:59:20ZengWileyLaryngoscope Investigative Otolaryngology2378-80382022-08-01741171117710.1002/lio2.862Verification EVestG recordings are vestibuloacoustic signalsBrian Blakley0Mehrangiz Ashiri1Zahra Moussavi2Brian Lithgow3Department of Otolaryngology Health Sciences Center, University of Manitoba St. Winnipeg Manitoba CanadaUniversity of Manitoba Winnipeg Manitoba CanadaUniversity of Manitoba Winnipeg Manitoba CanadaUniversity of Manitoba Winnipeg Manitoba CanadaAbstract Introduction Neural dysfunction is associated with aberrant nerve firing; thus, electrodiagnosis has the potential for objective diagnosis and quantification of neural dysfunction. Electrical stimulation alters nerve firing and may also have treatment potential. This article outlines some findings related to electrodiagnosis and electrical stimulation of the ear. The quasi‐synchronous firing of many vestibuloacoustic nerve fibers can produce an extracellular potential defined as a field potential (FP). Electrovestibulography (EVestG) is a method to record vestibuloacoustic signals and detect the associated FPs. A clear picture of the muscle‐, EEG‐, saccade‐related, or other artefactual origins, and the physiologic basis of FPs recorded with EVestG, is evolving. EVestG was applied to demonstrate the effect of electrical stimulation on spontaneous FPs in the ear canal. Methods Bilateral EVestG recordings were conducted on 14 guinea pigs before and after stimulation with 3–0.5 mA ipsilateral anodal electrical pulses before and after ablation via unilateral Scarpa's ganglionectomy to elucidate the origin of the EVestG recorded spontaneous FPs. Results Anodal electrical stimulation suppresses the recorded activity. There was a significant reduction of the level of recorded signal observed following anodal stimulation on the ablated but not the intact side. Conclusion Electrical stimulation of the external auditory canal reduces spontaneous electrical activity in the ear canal, some of which is due to central nervous system activity. The EVestG recorded FPs have a major vestibuloacoustic component.https://doi.org/10.1002/lio2.862acousticelectrical stimulationelectrovestibulographyEVestGvestibular |
| spellingShingle | Brian Blakley Mehrangiz Ashiri Zahra Moussavi Brian Lithgow Verification EVestG recordings are vestibuloacoustic signals Laryngoscope Investigative Otolaryngology acoustic electrical stimulation electrovestibulography EVestG vestibular |
| title | Verification EVestG recordings are vestibuloacoustic signals |
| title_full | Verification EVestG recordings are vestibuloacoustic signals |
| title_fullStr | Verification EVestG recordings are vestibuloacoustic signals |
| title_full_unstemmed | Verification EVestG recordings are vestibuloacoustic signals |
| title_short | Verification EVestG recordings are vestibuloacoustic signals |
| title_sort | verification evestg recordings are vestibuloacoustic signals |
| topic | acoustic electrical stimulation electrovestibulography EVestG vestibular |
| url | https://doi.org/10.1002/lio2.862 |
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