Intermittent theta-burst stimulation combined with transcranial direct current stimulation once weekly for treatment-resistant depression: a case report
Abstract Background Single-time non-invasive brain stimulation was carried out using the two-technique approach on a patient suffering from treatment-resistant depression. Five treatment sessions given at weekly intervals resulted in a significant improvement in the Patient Health Questionnaire-9 sc...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-10-01
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| Series: | Journal of Medical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13256-023-04152-0 |
| _version_ | 1797219792496623616 |
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| author | Pakorn Wivatvongvana Chutimon Soonthornthum Kittipong Kitisak |
| author_facet | Pakorn Wivatvongvana Chutimon Soonthornthum Kittipong Kitisak |
| author_sort | Pakorn Wivatvongvana |
| collection | DOAJ |
| description | Abstract Background Single-time non-invasive brain stimulation was carried out using the two-technique approach on a patient suffering from treatment-resistant depression. Five treatment sessions given at weekly intervals resulted in a significant improvement in the Patient Health Questionnaire-9 score for up to 6 weeks. The findings of this study could pave the way for a more efficient less resource-intensive time- and budget-saving technique of employing non-invasive brain stimulation for patients with treatment-resistant depression by minimizing the number of stimulation sessions. Case presentation A 67-year-old married non-Latino white American woman suffering from treatment-resistant depression received intermittent theta-burst stimulation in combination with transcranial direct current stimulation weekly for 5 consecutive weeks. Diagnostic transcranial magnetic stimulation showed an observable electrophysiological change. The patient reported a drastic improvement in Patient Health Questionnaire-9 score up until 6-week follow-up and expressed satisfaction with the treatment. Conclusions This case study suggests that a streamlined protocol for using non-invasive brain stimulation could prove more effective for patients and healthcare providers in terms of safety in comparison to the present guidelines. |
| first_indexed | 2024-03-10T17:45:48Z |
| format | Article |
| id | doaj.art-4ffa2aa4dd984f7dace43f0500e134c1 |
| institution | Directory Open Access Journal |
| issn | 1752-1947 |
| language | English |
| last_indexed | 2024-04-24T12:39:17Z |
| publishDate | 2023-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Medical Case Reports |
| spelling | doaj.art-4ffa2aa4dd984f7dace43f0500e134c12024-04-07T11:19:45ZengBMCJournal of Medical Case Reports1752-19472023-10-011711510.1186/s13256-023-04152-0Intermittent theta-burst stimulation combined with transcranial direct current stimulation once weekly for treatment-resistant depression: a case reportPakorn Wivatvongvana0Chutimon Soonthornthum1Kittipong Kitisak2Department of Rehabilitation Medicine, Faculty of Medicine, Chiang Mai UniversityDepartment of Rehabilitation Medicine, Faculty of Medicine, Chiang Mai UniversityDepartment of Rehabilitation Medicine, Faculty of Medicine, Chiang Mai UniversityAbstract Background Single-time non-invasive brain stimulation was carried out using the two-technique approach on a patient suffering from treatment-resistant depression. Five treatment sessions given at weekly intervals resulted in a significant improvement in the Patient Health Questionnaire-9 score for up to 6 weeks. The findings of this study could pave the way for a more efficient less resource-intensive time- and budget-saving technique of employing non-invasive brain stimulation for patients with treatment-resistant depression by minimizing the number of stimulation sessions. Case presentation A 67-year-old married non-Latino white American woman suffering from treatment-resistant depression received intermittent theta-burst stimulation in combination with transcranial direct current stimulation weekly for 5 consecutive weeks. Diagnostic transcranial magnetic stimulation showed an observable electrophysiological change. The patient reported a drastic improvement in Patient Health Questionnaire-9 score up until 6-week follow-up and expressed satisfaction with the treatment. Conclusions This case study suggests that a streamlined protocol for using non-invasive brain stimulation could prove more effective for patients and healthcare providers in terms of safety in comparison to the present guidelines.https://doi.org/10.1186/s13256-023-04152-0Treatment-resistant depressioniTBSTMStDCSPHQ-9 |
| spellingShingle | Pakorn Wivatvongvana Chutimon Soonthornthum Kittipong Kitisak Intermittent theta-burst stimulation combined with transcranial direct current stimulation once weekly for treatment-resistant depression: a case report Journal of Medical Case Reports Treatment-resistant depression iTBS TMS tDCS PHQ-9 |
| title | Intermittent theta-burst stimulation combined with transcranial direct current stimulation once weekly for treatment-resistant depression: a case report |
| title_full | Intermittent theta-burst stimulation combined with transcranial direct current stimulation once weekly for treatment-resistant depression: a case report |
| title_fullStr | Intermittent theta-burst stimulation combined with transcranial direct current stimulation once weekly for treatment-resistant depression: a case report |
| title_full_unstemmed | Intermittent theta-burst stimulation combined with transcranial direct current stimulation once weekly for treatment-resistant depression: a case report |
| title_short | Intermittent theta-burst stimulation combined with transcranial direct current stimulation once weekly for treatment-resistant depression: a case report |
| title_sort | intermittent theta burst stimulation combined with transcranial direct current stimulation once weekly for treatment resistant depression a case report |
| topic | Treatment-resistant depression iTBS TMS tDCS PHQ-9 |
| url | https://doi.org/10.1186/s13256-023-04152-0 |
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