Effects of micro-porosity and local BMP-2 administration on bioresorption of β-TCP and new bone formation

Effects of micro-porosity and local BMP-2 administration on bioresorption of β-TCP and new bone formation

Abstract Background It has been reported that the microporous structure of calcium phosphate (CaP) ceramics is important to osteoconduction. Bone morphogenetic protein-2 (BMP-2) has been shown to be a promising alternative to bone grafting and a therapeutic agent promoting bone regeneration when del...

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Bibliographic Details
Main Authors: Atsuhito Kakuta, Takaaki Tanaka, Masaaki Chazono, Hirokazu Komaki, Seiichiro Kitasato, Naoya Inagaki, Shoshi Akiyama, Keishi Marumo
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2019-07-01
Series:Biomaterials Research
Subjects:
Beta-tricalcium phosphate (β-TCP)
Microporous structure
Bone morphogenetic protein (BMP)
Bone formation
Osteoclasts
Online Access:http://link.springer.com/article/10.1186/s40824-019-0161-2

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