Stimuli-Responsive Gene Delivery Nanocarriers for Cancer Therapy

Highlights Stimuli-responsive gene delivery nanocarriers (GDNCs) possess huge potential in the gene therapy field owing to their effective protection, prolonged blood circulation, selective and targeted delivery, and controlled release of nucleic acid drugs. Recent advances in stimuli-responsive GDN...

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Main Authors: Qingfei Zhang, Gaizhen Kuang, Wenzhao Li, Jinglin Wang, Haozhen Ren, Yuanjin Zhao
Format: Article
Language:English
Published: SpringerOpen 2023-02-01
Series:Nano-Micro Letters
Subjects:
Online Access:https://doi.org/10.1007/s40820-023-01018-4
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author Qingfei Zhang
Gaizhen Kuang
Wenzhao Li
Jinglin Wang
Haozhen Ren
Yuanjin Zhao
author_facet Qingfei Zhang
Gaizhen Kuang
Wenzhao Li
Jinglin Wang
Haozhen Ren
Yuanjin Zhao
author_sort Qingfei Zhang
collection DOAJ
description Highlights Stimuli-responsive gene delivery nanocarriers (GDNCs) possess huge potential in the gene therapy field owing to their effective protection, prolonged blood circulation, selective and targeted delivery, and controlled release of nucleic acid drugs. Recent advances in stimuli-responsive GDNCs for cancer therapy are classified, summarized, and exhibited by representative examples. The potential challenges and prospects of stimuli-responsive GDNCs toward clinical translation are outlined and the future research directions are outlooked.
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spelling doaj.art-5000036f6e8a4a76850167dd53c6c9142023-11-20T10:38:51ZengSpringerOpenNano-Micro Letters2311-67062150-55512023-02-0115113310.1007/s40820-023-01018-4Stimuli-Responsive Gene Delivery Nanocarriers for Cancer TherapyQingfei Zhang0Gaizhen Kuang1Wenzhao Li2Jinglin Wang3Haozhen Ren4Yuanjin Zhao5Department of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Hepatobiliary Institute of Nanjing UniversityDepartment of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Hepatobiliary Institute of Nanjing UniversityDepartment of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Hepatobiliary Institute of Nanjing UniversityDepartment of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Hepatobiliary Institute of Nanjing UniversityDepartment of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Hepatobiliary Institute of Nanjing UniversityDepartment of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Hepatobiliary Institute of Nanjing UniversityHighlights Stimuli-responsive gene delivery nanocarriers (GDNCs) possess huge potential in the gene therapy field owing to their effective protection, prolonged blood circulation, selective and targeted delivery, and controlled release of nucleic acid drugs. Recent advances in stimuli-responsive GDNCs for cancer therapy are classified, summarized, and exhibited by representative examples. The potential challenges and prospects of stimuli-responsive GDNCs toward clinical translation are outlined and the future research directions are outlooked.https://doi.org/10.1007/s40820-023-01018-4Stimuli-responsiveNanocarrierGene therapyGene deliveryCancer
spellingShingle Qingfei Zhang
Gaizhen Kuang
Wenzhao Li
Jinglin Wang
Haozhen Ren
Yuanjin Zhao
Stimuli-Responsive Gene Delivery Nanocarriers for Cancer Therapy
Nano-Micro Letters
Stimuli-responsive
Nanocarrier
Gene therapy
Gene delivery
Cancer
title Stimuli-Responsive Gene Delivery Nanocarriers for Cancer Therapy
title_full Stimuli-Responsive Gene Delivery Nanocarriers for Cancer Therapy
title_fullStr Stimuli-Responsive Gene Delivery Nanocarriers for Cancer Therapy
title_full_unstemmed Stimuli-Responsive Gene Delivery Nanocarriers for Cancer Therapy
title_short Stimuli-Responsive Gene Delivery Nanocarriers for Cancer Therapy
title_sort stimuli responsive gene delivery nanocarriers for cancer therapy
topic Stimuli-responsive
Nanocarrier
Gene therapy
Gene delivery
Cancer
url https://doi.org/10.1007/s40820-023-01018-4
work_keys_str_mv AT qingfeizhang stimuliresponsivegenedeliverynanocarriersforcancertherapy
AT gaizhenkuang stimuliresponsivegenedeliverynanocarriersforcancertherapy
AT wenzhaoli stimuliresponsivegenedeliverynanocarriersforcancertherapy
AT jinglinwang stimuliresponsivegenedeliverynanocarriersforcancertherapy
AT haozhenren stimuliresponsivegenedeliverynanocarriersforcancertherapy
AT yuanjinzhao stimuliresponsivegenedeliverynanocarriersforcancertherapy