Stimuli-Responsive Gene Delivery Nanocarriers for Cancer Therapy
Highlights Stimuli-responsive gene delivery nanocarriers (GDNCs) possess huge potential in the gene therapy field owing to their effective protection, prolonged blood circulation, selective and targeted delivery, and controlled release of nucleic acid drugs. Recent advances in stimuli-responsive GDN...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
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SpringerOpen
2023-02-01
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Series: | Nano-Micro Letters |
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Online Access: | https://doi.org/10.1007/s40820-023-01018-4 |
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author | Qingfei Zhang Gaizhen Kuang Wenzhao Li Jinglin Wang Haozhen Ren Yuanjin Zhao |
author_facet | Qingfei Zhang Gaizhen Kuang Wenzhao Li Jinglin Wang Haozhen Ren Yuanjin Zhao |
author_sort | Qingfei Zhang |
collection | DOAJ |
description | Highlights Stimuli-responsive gene delivery nanocarriers (GDNCs) possess huge potential in the gene therapy field owing to their effective protection, prolonged blood circulation, selective and targeted delivery, and controlled release of nucleic acid drugs. Recent advances in stimuli-responsive GDNCs for cancer therapy are classified, summarized, and exhibited by representative examples. The potential challenges and prospects of stimuli-responsive GDNCs toward clinical translation are outlined and the future research directions are outlooked. |
first_indexed | 2024-03-10T17:10:58Z |
format | Article |
id | doaj.art-5000036f6e8a4a76850167dd53c6c914 |
institution | Directory Open Access Journal |
issn | 2311-6706 2150-5551 |
language | English |
last_indexed | 2024-03-10T17:10:58Z |
publishDate | 2023-02-01 |
publisher | SpringerOpen |
record_format | Article |
series | Nano-Micro Letters |
spelling | doaj.art-5000036f6e8a4a76850167dd53c6c9142023-11-20T10:38:51ZengSpringerOpenNano-Micro Letters2311-67062150-55512023-02-0115113310.1007/s40820-023-01018-4Stimuli-Responsive Gene Delivery Nanocarriers for Cancer TherapyQingfei Zhang0Gaizhen Kuang1Wenzhao Li2Jinglin Wang3Haozhen Ren4Yuanjin Zhao5Department of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Hepatobiliary Institute of Nanjing UniversityDepartment of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Hepatobiliary Institute of Nanjing UniversityDepartment of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Hepatobiliary Institute of Nanjing UniversityDepartment of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Hepatobiliary Institute of Nanjing UniversityDepartment of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Hepatobiliary Institute of Nanjing UniversityDepartment of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Hepatobiliary Institute of Nanjing UniversityHighlights Stimuli-responsive gene delivery nanocarriers (GDNCs) possess huge potential in the gene therapy field owing to their effective protection, prolonged blood circulation, selective and targeted delivery, and controlled release of nucleic acid drugs. Recent advances in stimuli-responsive GDNCs for cancer therapy are classified, summarized, and exhibited by representative examples. The potential challenges and prospects of stimuli-responsive GDNCs toward clinical translation are outlined and the future research directions are outlooked.https://doi.org/10.1007/s40820-023-01018-4Stimuli-responsiveNanocarrierGene therapyGene deliveryCancer |
spellingShingle | Qingfei Zhang Gaizhen Kuang Wenzhao Li Jinglin Wang Haozhen Ren Yuanjin Zhao Stimuli-Responsive Gene Delivery Nanocarriers for Cancer Therapy Nano-Micro Letters Stimuli-responsive Nanocarrier Gene therapy Gene delivery Cancer |
title | Stimuli-Responsive Gene Delivery Nanocarriers for Cancer Therapy |
title_full | Stimuli-Responsive Gene Delivery Nanocarriers for Cancer Therapy |
title_fullStr | Stimuli-Responsive Gene Delivery Nanocarriers for Cancer Therapy |
title_full_unstemmed | Stimuli-Responsive Gene Delivery Nanocarriers for Cancer Therapy |
title_short | Stimuli-Responsive Gene Delivery Nanocarriers for Cancer Therapy |
title_sort | stimuli responsive gene delivery nanocarriers for cancer therapy |
topic | Stimuli-responsive Nanocarrier Gene therapy Gene delivery Cancer |
url | https://doi.org/10.1007/s40820-023-01018-4 |
work_keys_str_mv | AT qingfeizhang stimuliresponsivegenedeliverynanocarriersforcancertherapy AT gaizhenkuang stimuliresponsivegenedeliverynanocarriersforcancertherapy AT wenzhaoli stimuliresponsivegenedeliverynanocarriersforcancertherapy AT jinglinwang stimuliresponsivegenedeliverynanocarriersforcancertherapy AT haozhenren stimuliresponsivegenedeliverynanocarriersforcancertherapy AT yuanjinzhao stimuliresponsivegenedeliverynanocarriersforcancertherapy |