Significance of tumor heterogeneity of p-Smad2 and c-Met in HER2-positive gastric carcinoma with lymph node metastasis

Significance of tumor heterogeneity of p-Smad2 and c-Met in HER2-positive gastric carcinoma with lymph node metastasis

Abstract Background Tumor heterogeneity has frequently been observed in gastric cancer (GC), but the correlation between patients’ clinico-pathologic features and the tumoral heterogeneity of GC-associated molecules is unclear. We investigated the correlation between lymph node metastasis and the in...

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Bibliographic Details
Main Authors: Gen Tsujio, Koji Maruo, Yurie Yamamoto, Tomohiro Sera, Atsushi Sugimoto, Hiroaki Kasashima, Yuichiro Miki, Mami Yoshii, Tatsuro Tamura, Takahiro Toyokawa, Hiroaki Tanaka, Kazuya Muguruma, Masaichi Ohira, Masakazu Yashiro
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Cancer
Subjects:
Gastric cancer
Intra-tumoral heterogeneity
Clustering analysis
Online Access:https://doi.org/10.1186/s12885-022-09681-3

Internet

https://doi.org/10.1186/s12885-022-09681-3

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