Integration of hydrogels in microfabrication processes for bioelectronic medicine: Progress and outlook
Recent research aiming at the development of electroceuticals for the treatment of medical conditions such as degenerative diseases, cardiac arrhythmia and chronic pain, has given rise to microfabricated implanted bioelectronic devices capable of interacting with host biological tissues in synergist...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2023-03-01
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Series: | Frontiers in Bioengineering and Biotechnology |
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Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2023.1150147/full |
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author | Saloua Saghir Kristin Imenes Giuseppe Schiavone |
author_facet | Saloua Saghir Kristin Imenes Giuseppe Schiavone |
author_sort | Saloua Saghir |
collection | DOAJ |
description | Recent research aiming at the development of electroceuticals for the treatment of medical conditions such as degenerative diseases, cardiac arrhythmia and chronic pain, has given rise to microfabricated implanted bioelectronic devices capable of interacting with host biological tissues in synergistic modalities. Owing to their multimodal affinity to biological tissues, hydrogels have emerged as promising interface materials for bioelectronic devices. Here, we review the state-of-the-art and forefront in the techniques used by research groups for the integration of hydrogels into the microfabrication processes of bioelectronic devices, and present the manufacturability challenges to unlock their further clinical deployment. |
first_indexed | 2024-04-09T21:56:17Z |
format | Article |
id | doaj.art-5011598cb042471295f72239350947a5 |
institution | Directory Open Access Journal |
issn | 2296-4185 |
language | English |
last_indexed | 2024-04-09T21:56:17Z |
publishDate | 2023-03-01 |
publisher | Frontiers Media S.A. |
record_format | Article |
series | Frontiers in Bioengineering and Biotechnology |
spelling | doaj.art-5011598cb042471295f72239350947a52023-03-24T05:18:02ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852023-03-011110.3389/fbioe.2023.11501471150147Integration of hydrogels in microfabrication processes for bioelectronic medicine: Progress and outlookSaloua SaghirKristin ImenesGiuseppe SchiavoneRecent research aiming at the development of electroceuticals for the treatment of medical conditions such as degenerative diseases, cardiac arrhythmia and chronic pain, has given rise to microfabricated implanted bioelectronic devices capable of interacting with host biological tissues in synergistic modalities. Owing to their multimodal affinity to biological tissues, hydrogels have emerged as promising interface materials for bioelectronic devices. Here, we review the state-of-the-art and forefront in the techniques used by research groups for the integration of hydrogels into the microfabrication processes of bioelectronic devices, and present the manufacturability challenges to unlock their further clinical deployment.https://www.frontiersin.org/articles/10.3389/fbioe.2023.1150147/fullhydrogelsbioelectronic interfacesmicrofabrication processesimplantable medical devicesbiomaterialssoft bioelectronics |
spellingShingle | Saloua Saghir Kristin Imenes Giuseppe Schiavone Integration of hydrogels in microfabrication processes for bioelectronic medicine: Progress and outlook Frontiers in Bioengineering and Biotechnology hydrogels bioelectronic interfaces microfabrication processes implantable medical devices biomaterials soft bioelectronics |
title | Integration of hydrogels in microfabrication processes for bioelectronic medicine: Progress and outlook |
title_full | Integration of hydrogels in microfabrication processes for bioelectronic medicine: Progress and outlook |
title_fullStr | Integration of hydrogels in microfabrication processes for bioelectronic medicine: Progress and outlook |
title_full_unstemmed | Integration of hydrogels in microfabrication processes for bioelectronic medicine: Progress and outlook |
title_short | Integration of hydrogels in microfabrication processes for bioelectronic medicine: Progress and outlook |
title_sort | integration of hydrogels in microfabrication processes for bioelectronic medicine progress and outlook |
topic | hydrogels bioelectronic interfaces microfabrication processes implantable medical devices biomaterials soft bioelectronics |
url | https://www.frontiersin.org/articles/10.3389/fbioe.2023.1150147/full |
work_keys_str_mv | AT salouasaghir integrationofhydrogelsinmicrofabricationprocessesforbioelectronicmedicineprogressandoutlook AT kristinimenes integrationofhydrogelsinmicrofabricationprocessesforbioelectronicmedicineprogressandoutlook AT giuseppeschiavone integrationofhydrogelsinmicrofabricationprocessesforbioelectronicmedicineprogressandoutlook |