Primary porcine fibroblasts: Ochratoxin A cytotoxicity and role of all-trans-retinol and alpha-tocopherol
Ochratoxin A (OTA) is a mycotoxin produced by Aspergillus and Penicillium species and it is a contaminant of food and feeds (O’Brien et al., 2001). OTA is a nephrotoxic, carcinogenic and teratogenic compound and one of the most sensible species among domestic animals is the pig (JECFA, 200...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2010-01-01
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| Series: | Italian Journal of Animal Science |
| Subjects: | |
| Online Access: | http://www.aspajournal.it/index.php/ijas/article/view/811 |
| _version_ | 1818032006042222592 |
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| author | A. Baldi K. Sejrsen S. Purup L. Sangalli R. Rebucci E. Fusi |
| author_facet | A. Baldi K. Sejrsen S. Purup L. Sangalli R. Rebucci E. Fusi |
| author_sort | A. Baldi |
| collection | DOAJ |
| description | Ochratoxin A (OTA) is a mycotoxin produced by Aspergillus and Penicillium species and it is a contaminant of food and feeds (O’Brien et al., 2001). OTA is a nephrotoxic, carcinogenic and teratogenic compound and one of the most sensible species among domestic animals is the pig (JECFA, 2001). Production of free radicals or reactive oxygen species (ROS) leading to lipid peroxidation was suggested to be one of the mechanisms by which OTA damages the cell (Rahimtula et al., 1988). |
| first_indexed | 2024-12-10T06:00:30Z |
| format | Article |
| id | doaj.art-5012d1d4da9247be84b09a3c34e9f30e |
| institution | Directory Open Access Journal |
| issn | 1594-4077 1828-051X |
| language | English |
| last_indexed | 2024-12-10T06:00:30Z |
| publishDate | 2010-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Italian Journal of Animal Science |
| spelling | doaj.art-5012d1d4da9247be84b09a3c34e9f30e2022-12-22T01:59:49ZengTaylor & Francis GroupItalian Journal of Animal Science1594-40771828-051X2010-01-0142s48548710.4081/ijas.2005.2s.485Primary porcine fibroblasts: Ochratoxin A cytotoxicity and role of all-trans-retinol and alpha-tocopherolA. BaldiK. SejrsenS. PurupL. SangalliR. RebucciE. FusiOchratoxin A (OTA) is a mycotoxin produced by Aspergillus and Penicillium species and it is a contaminant of food and feeds (O’Brien et al., 2001). OTA is a nephrotoxic, carcinogenic and teratogenic compound and one of the most sensible species among domestic animals is the pig (JECFA, 2001). Production of free radicals or reactive oxygen species (ROS) leading to lipid peroxidation was suggested to be one of the mechanisms by which OTA damages the cell (Rahimtula et al., 1988).http://www.aspajournal.it/index.php/ijas/article/view/811fibroblasts, ochratoxin A, cytotoxicity, antioxidants |
| spellingShingle | A. Baldi K. Sejrsen S. Purup L. Sangalli R. Rebucci E. Fusi Primary porcine fibroblasts: Ochratoxin A cytotoxicity and role of all-trans-retinol and alpha-tocopherol Italian Journal of Animal Science fibroblasts, ochratoxin A, cytotoxicity, antioxidants |
| title | Primary porcine fibroblasts: Ochratoxin A cytotoxicity and role of all-trans-retinol and alpha-tocopherol |
| title_full | Primary porcine fibroblasts: Ochratoxin A cytotoxicity and role of all-trans-retinol and alpha-tocopherol |
| title_fullStr | Primary porcine fibroblasts: Ochratoxin A cytotoxicity and role of all-trans-retinol and alpha-tocopherol |
| title_full_unstemmed | Primary porcine fibroblasts: Ochratoxin A cytotoxicity and role of all-trans-retinol and alpha-tocopherol |
| title_short | Primary porcine fibroblasts: Ochratoxin A cytotoxicity and role of all-trans-retinol and alpha-tocopherol |
| title_sort | primary porcine fibroblasts ochratoxin a cytotoxicity and role of all trans retinol and alpha tocopherol |
| topic | fibroblasts, ochratoxin A, cytotoxicity, antioxidants |
| url | http://www.aspajournal.it/index.php/ijas/article/view/811 |
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