Correlation between admission hypoalbuminemia and postoperative urinary tract infections in elderly hip fracture patients
Abstract Purpose This study aimed to evaluate the correlation between hypoalbuminemia upon admission and the incidence of postoperative urinary tract infections (UTIs) in elderly patients with hip fractures. Methods A retrospective analysis was performed on the medical records of elderly patients wh...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-10-01
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| Series: | Journal of Orthopaedic Surgery and Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13018-023-04274-7 |
| _version_ | 1797452032946208768 |
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| author | Wei Yao Wanyun Tang Wei Wang Qiaomei Lv Wenbo Ding |
| author_facet | Wei Yao Wanyun Tang Wei Wang Qiaomei Lv Wenbo Ding |
| author_sort | Wei Yao |
| collection | DOAJ |
| description | Abstract Purpose This study aimed to evaluate the correlation between hypoalbuminemia upon admission and the incidence of postoperative urinary tract infections (UTIs) in elderly patients with hip fractures. Methods A retrospective analysis was performed on the medical records of elderly patients who underwent surgical treatment for hip fractures at a level I trauma center from 2013 to 2023. Serum albumin levels were measured upon admission, and hypoalbuminemia was defined as a total albumin level < 35 g/L. Multivariable logistic regression and propensity score matching analysis were utilized to control and reduce potential confounding factors, aiming to obtain adjusted odds ratios (ORs) and 95% confidence intervals (CI) for UTIs to determine the strength of the association. Results This observational cohort study included 1279 patients, among whom 298 (23.3%) developed UTIs. Patients with albumin levels < 35 g/L had significantly greater odds of developing UTIs compared to those with albumin levels ≥ 35 g/L (OR 1.86, 95% CI 1.28–2.70). Further analysis, dividing albumin levels into quartiles, demonstrated that patients in the Q2 group (38.0–40.9 g/L; OR 1.38, 95% CI 0.88–2.17), Q3 group (35.0–37.9 g/L; OR 1.69, 95% CI 1.06–2.71), and Q4 group (15.3–34.9 g/L; OR 2.67, 95% CI 1.61–4.43) had notably higher odds of developing UTIs compared to those in the Q1 group (41.0–52.0 g/L). Conclusions The presence of hypoalbuminemia upon admission in elderly patients undergoing hip fracture surgery is strongly correlated with the occurrence of postoperative UTIs. Furthermore, this association exhibits a clear dose–response relationship. |
| first_indexed | 2024-03-09T15:02:55Z |
| format | Article |
| id | doaj.art-501397776a234a888762f5733aa93027 |
| institution | Directory Open Access Journal |
| issn | 1749-799X |
| language | English |
| last_indexed | 2024-03-09T15:02:55Z |
| publishDate | 2023-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Orthopaedic Surgery and Research |
| spelling | doaj.art-501397776a234a888762f5733aa930272023-11-26T13:49:22ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2023-10-0118111110.1186/s13018-023-04274-7Correlation between admission hypoalbuminemia and postoperative urinary tract infections in elderly hip fracture patientsWei Yao0Wanyun Tang1Wei Wang2Qiaomei Lv3Wenbo Ding4Department of Orthopedics, Dandong Central Hospital, China Medical UniversityDepartment of Orthopedics, Dandong Central Hospital, China Medical UniversityDepartment of Orthopedics, Dandong Central Hospital, China Medical UniversityDepartment of Oncology, Dandong Central Hospital, China Medical UniversityDepartment of Orthopedics, Dandong Central Hospital, China Medical UniversityAbstract Purpose This study aimed to evaluate the correlation between hypoalbuminemia upon admission and the incidence of postoperative urinary tract infections (UTIs) in elderly patients with hip fractures. Methods A retrospective analysis was performed on the medical records of elderly patients who underwent surgical treatment for hip fractures at a level I trauma center from 2013 to 2023. Serum albumin levels were measured upon admission, and hypoalbuminemia was defined as a total albumin level < 35 g/L. Multivariable logistic regression and propensity score matching analysis were utilized to control and reduce potential confounding factors, aiming to obtain adjusted odds ratios (ORs) and 95% confidence intervals (CI) for UTIs to determine the strength of the association. Results This observational cohort study included 1279 patients, among whom 298 (23.3%) developed UTIs. Patients with albumin levels < 35 g/L had significantly greater odds of developing UTIs compared to those with albumin levels ≥ 35 g/L (OR 1.86, 95% CI 1.28–2.70). Further analysis, dividing albumin levels into quartiles, demonstrated that patients in the Q2 group (38.0–40.9 g/L; OR 1.38, 95% CI 0.88–2.17), Q3 group (35.0–37.9 g/L; OR 1.69, 95% CI 1.06–2.71), and Q4 group (15.3–34.9 g/L; OR 2.67, 95% CI 1.61–4.43) had notably higher odds of developing UTIs compared to those in the Q1 group (41.0–52.0 g/L). Conclusions The presence of hypoalbuminemia upon admission in elderly patients undergoing hip fracture surgery is strongly correlated with the occurrence of postoperative UTIs. Furthermore, this association exhibits a clear dose–response relationship.https://doi.org/10.1186/s13018-023-04274-7Hip fractureElderlyHypoalbuminemiaUrinary tract infectionsRisk factors |
| spellingShingle | Wei Yao Wanyun Tang Wei Wang Qiaomei Lv Wenbo Ding Correlation between admission hypoalbuminemia and postoperative urinary tract infections in elderly hip fracture patients Journal of Orthopaedic Surgery and Research Hip fracture Elderly Hypoalbuminemia Urinary tract infections Risk factors |
| title | Correlation between admission hypoalbuminemia and postoperative urinary tract infections in elderly hip fracture patients |
| title_full | Correlation between admission hypoalbuminemia and postoperative urinary tract infections in elderly hip fracture patients |
| title_fullStr | Correlation between admission hypoalbuminemia and postoperative urinary tract infections in elderly hip fracture patients |
| title_full_unstemmed | Correlation between admission hypoalbuminemia and postoperative urinary tract infections in elderly hip fracture patients |
| title_short | Correlation between admission hypoalbuminemia and postoperative urinary tract infections in elderly hip fracture patients |
| title_sort | correlation between admission hypoalbuminemia and postoperative urinary tract infections in elderly hip fracture patients |
| topic | Hip fracture Elderly Hypoalbuminemia Urinary tract infections Risk factors |
| url | https://doi.org/10.1186/s13018-023-04274-7 |
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