Study of clinical and biochemical profile of scrub typhus in a tertiary care hospital of West Bengal
Background: Humans are accidental hosts in the zoonotic disease Scrub typhus. The disease though widespread in our county, it remains grossly underdiagnosed because of its non-septic clinical manifestations and lack of access to specific laboratory facilities. Aims and Objectives: The objective o...
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| Format: | Article |
| Language: | English |
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Manipal College of Medical Sciences, Pokhara
2023-07-01
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| Series: | Asian Journal of Medical Sciences |
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| Online Access: | https://www.nepjol.info/index.php/AJMS/article/view/53188 |
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| author | Rakesh Mandal Sarmila Guha Banerjee Arunima Sinha Ujjwal Bandyopadhyay Arijit Sinha |
| author_facet | Rakesh Mandal Sarmila Guha Banerjee Arunima Sinha Ujjwal Bandyopadhyay Arijit Sinha |
| author_sort | Rakesh Mandal |
| collection | DOAJ |
| description | Background: Humans are accidental hosts in the zoonotic disease Scrub typhus. The disease though widespread in our county, it remains grossly underdiagnosed because of its non-septic clinical manifestations and lack of access to specific laboratory facilities.
Aims and Objectives: The objective of present study is to evaluate the clinical presentations of Scrub Typhus among the study group. Furthermore, to assess the various laboratory findings in Scrub Typhus cases among the study group is the other objective of this study.
Materials and Methods: The present study is an Institution-based, observational, and cross-sectional study conducted for 18 months with the admitted patients having 14–70 years of age. Data collected regarding patients’ demographic profile, symptoms, clinical findings, laboratory, and radiological findings. Data had been summarized as mean and standard deviation for numerical variables and count and percentages for categorical variables.
Results: In our study, we found that most of the patients were 14–20 years old and female population was higher. It was found that 34.3% of patients had Eschar, 42.9% of patients had Rash, and 91.4% of patients had Pallor, 8.6% of patients had Ascites, 25.7% had Edema, 8.6% of patients had Jaundice, 11.4% had shock, and 57.1% had pneumonia/pneumonitis. The present study showed that 65.7% of patients had drug response (Doxycycline).
Conclusion: Knowledge of geographical distribution, evidence of exposure to vector, clinical features such as fever, rash, eschar, headache, and myalgia along with high index of suspicion are crucial factors for early diagnosis and that helps in timely treatment of the cases. |
| first_indexed | 2024-03-13T02:00:08Z |
| format | Article |
| id | doaj.art-501593716047452fbd9778c5866b7ce2 |
| institution | Directory Open Access Journal |
| issn | 2467-9100 2091-0576 |
| language | English |
| last_indexed | 2024-03-13T02:00:08Z |
| publishDate | 2023-07-01 |
| publisher | Manipal College of Medical Sciences, Pokhara |
| record_format | Article |
| series | Asian Journal of Medical Sciences |
| spelling | doaj.art-501593716047452fbd9778c5866b7ce22023-07-02T03:26:17ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762023-07-011479398https://doi.org/10.3126/ajms.v14i7.53188Study of clinical and biochemical profile of scrub typhus in a tertiary care hospital of West BengalRakesh Mandal 0https://orcid.org/0009-0004-8009-4154Sarmila Guha Banerjee 1https://orcid.org/0009-0007-9091-3143Arunima Sinha 2https://orcid.org/0009-0003-7931-4204Ujjwal Bandyopadhyay 3https://orcid.org/0009-0004-1161-4689Arijit Sinha 4https://orcid.org/0000-0001-8667-4601Medical Officer, Department of Medicine, Haldia Sub Division Hospital, Haldia, West Bengal, India Associate Professor, Department of Anesthesiology, Calcutta Medical College, Kolkata, West Bengal, India Student, Department of Biotechnology, Heritage Institute of Technology, Haldia, West Bengal, India Associate Professor, Department of Pathology, Raiganj Government Medical College, Raiganj, West Bengal, India Professor, Department of Medicine, Nilratan Sircar Medical College, Kolkata, West Bengal, India Background: Humans are accidental hosts in the zoonotic disease Scrub typhus. The disease though widespread in our county, it remains grossly underdiagnosed because of its non-septic clinical manifestations and lack of access to specific laboratory facilities. Aims and Objectives: The objective of present study is to evaluate the clinical presentations of Scrub Typhus among the study group. Furthermore, to assess the various laboratory findings in Scrub Typhus cases among the study group is the other objective of this study. Materials and Methods: The present study is an Institution-based, observational, and cross-sectional study conducted for 18 months with the admitted patients having 14–70 years of age. Data collected regarding patients’ demographic profile, symptoms, clinical findings, laboratory, and radiological findings. Data had been summarized as mean and standard deviation for numerical variables and count and percentages for categorical variables. Results: In our study, we found that most of the patients were 14–20 years old and female population was higher. It was found that 34.3% of patients had Eschar, 42.9% of patients had Rash, and 91.4% of patients had Pallor, 8.6% of patients had Ascites, 25.7% had Edema, 8.6% of patients had Jaundice, 11.4% had shock, and 57.1% had pneumonia/pneumonitis. The present study showed that 65.7% of patients had drug response (Doxycycline). Conclusion: Knowledge of geographical distribution, evidence of exposure to vector, clinical features such as fever, rash, eschar, headache, and myalgia along with high index of suspicion are crucial factors for early diagnosis and that helps in timely treatment of the cases.https://www.nepjol.info/index.php/AJMS/article/view/53188clinical profile; eastern india; scrub typhus |
| spellingShingle | Rakesh Mandal Sarmila Guha Banerjee Arunima Sinha Ujjwal Bandyopadhyay Arijit Sinha Study of clinical and biochemical profile of scrub typhus in a tertiary care hospital of West Bengal Asian Journal of Medical Sciences clinical profile; eastern india; scrub typhus |
| title | Study of clinical and biochemical profile of scrub typhus in a tertiary care hospital of West Bengal |
| title_full | Study of clinical and biochemical profile of scrub typhus in a tertiary care hospital of West Bengal |
| title_fullStr | Study of clinical and biochemical profile of scrub typhus in a tertiary care hospital of West Bengal |
| title_full_unstemmed | Study of clinical and biochemical profile of scrub typhus in a tertiary care hospital of West Bengal |
| title_short | Study of clinical and biochemical profile of scrub typhus in a tertiary care hospital of West Bengal |
| title_sort | study of clinical and biochemical profile of scrub typhus in a tertiary care hospital of west bengal |
| topic | clinical profile; eastern india; scrub typhus |
| url | https://www.nepjol.info/index.php/AJMS/article/view/53188 |
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