Selective Survival of Sim1/MC4R Neurons in Diet-Induced Obesity

Selective Survival of Sim1/MC4R Neurons in Diet-Induced Obesity

Summary: In the melanocortin pathway, melanocortin-4 receptor (MC4R) functions to control energy homeostasis. MC4R is expressed in a sub-population of Sim1 neurons (Sim1/MC4R neurons) and functions in hypothalamic paraventricular nuclei (PVN) to control food intake. Mapping sites of hypothalamic inj...

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Bibliographic Details
Main Authors: Eugene Nyamugenda, Haven Griffin, Susan Russell, Kimberly A. Cooney, Nicholas S. Kowalczyk, Ishrar Islam, Kevin D. Phelan, Giulia Baldini
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:iScience
Subjects:
biological sciences
human physiology
and molecular neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220302996

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