Detection of Cell Types Contributing to Cancer From Circulating, Cell-Free Methylated DNA

Detection of Cell Types Contributing to Cancer From Circulating, Cell-Free Methylated DNA

Detection of cellular changes in tissue biopsies has been the basis for cancer diagnostics. However, tissue biopsies are invasive and limited by inaccuracies due to sampling locations, restricted sampling frequency, and poor representation of tissue heterogeneity. Liquid biopsies are emerging as a c...

Full description

Bibliographic Details
Main Authors:	Megan E. Barefoot, Netanel Loyfer, Amber J. Kiliti, A. Patrick McDeed, Tommy Kaplan, Anton Wellstein
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-07-01
Series:	Frontiers in Genetics
Subjects:	Cell-free DNA (cfDNA) cellular damage circulating tumor DNA (ctDNA) deconvolution liquid biopsy tissue-of-origin
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2021.671057/full

Similar Items

Using cfDNA and ctDNA as Oncologic Markers: A Path to Clinical Validation
by: Jonathan Dao, et al.
Published: (2023-08-01)

Evaluation of commercial kits for isolation and bisulfite conversion of circulating cell-free tumor DNA from blood
by: Stine H. Kresse, et al.
Published: (2023-09-01)

New Perspectives on the Importance of Cell-Free DNA Biology
by: Abel J. Bronkhorst, et al.
Published: (2022-09-01)

Can Liquid Biopsy Based on ctDNA/cfDNA Replace Tissue Biopsy for the Precision Treatment of EGFR-Mutated NSCLC?
by: Yi-Ze Li, et al.
Published: (2023-02-01)

Extracellular Vesicle-Derived DNA vs. CfDNA as a Biomarker for the Detection of Colon Cancer
by: Kavita Thakur, et al.
Published: (2021-07-01)

The evidence base for circulating tumour DNA blood-based biomarkers for the early detection of cancer: a systematic mapping review
by: Ian A. Cree, et al.
Published: (2017-10-01)

Liquid biopsy: current technology and clinical applications
by: Mina Nikanjam, et al.
Published: (2022-09-01)

Retrospective Evaluation of Somatic Alterations in Cell-Free DNA from Blood in Retinoblastoma
by: David H. Abramson, MD, et al.
Published: (2021-03-01)

Sensitive and Specific Analyses of Colorectal Cancer Recurrence through Multiplex superRCA Mutation Detection in Blood Plasma
by: Emma Sandberg, et al.
Published: (2024-01-01)

Circulating Tumor DNA in Head and Neck Squamous Cell Carcinoma: Association with Metabolic Tumor Burden Determined with FDG-PET/CT
by: Antti Silvoniemi, et al.
Published: (2023-08-01)

Liquid Biopsy &ndash; Possibilities for Monitoring&nbsp;the Therapeutic Response in Non-Small Cell Lung Cancer
by: Gabriela A. Raycheva, et al.
Published: (2021-12-01)

Liquid biopsy in T-cell lymphoma: biomarker detection techniques and clinical application
by: Zongyao Huang, et al.
Published: (2024-02-01)

Combining Solid and Liquid Biopsy for Therapy Monitoring in Esophageal Cancer
by: Florian Richter, et al.
Published: (2023-06-01)

Liquid Biopsy in Diagnosis and Prognosis of Non-Metastatic Prostate Cancer
by: Alexey S. Rzhevskiy, et al.
Published: (2022-12-01)

Liquid biopsy: New opportunities for precision medicine in hepatocellular carcinoma care
by: Inah Marie C. Aquino, et al.
Published: (2024-03-01)

Mutated circulating tumor DNA as a liquid biopsy in lung cancer detection and treatment
by: Martyna Filipska, et al.
Published: (2021-06-01)

Beyond the Blood: CSF-Derived cfDNA for Diagnosis and Characterization of CNS Tumors
by: Abbye E. McEwen, et al.
Published: (2020-02-01)

Detection of <i>ESR1</i> Mutations in Primary Tumors and Plasma Cell-Free DNA in High-Grade Serous Ovarian Carcinoma Patients
by: Dimitra Stergiopoulou, et al.
Published: (2022-08-01)

Rational Development of Liquid Biopsy Analysis in Renal Cell Carcinoma
by: Kate I. Glennon, et al.
Published: (2021-11-01)

The Role of Cell-Free DNA in Cancer Treatment Decision Making
by: András Telekes, et al.
Published: (2022-12-01)

Promises and Challenges of Predictive Blood Biomarkers for Locally Advanced Rectal Cancer Treated with Neoadjuvant Chemoradiotherapy
by: Joao Victor Machado Carvalho, et al.
Published: (2023-01-01)

Comprehensive Genomic Profiling of Circulating Cell-Free DNA Distinguishes Focal <i>MET</i> Amplification from Aneuploidy in Diverse Advanced Cancers
by: Yuichi Kumaki, et al.
Published: (2021-09-01)

International pilot external quality assessment scheme for analysis and reporting of circulating tumour DNA
by: Cleo Keppens, et al.
Published: (2018-08-01)

Technical Evaluation of Commercial Mutation Analysis Platforms and Reference Materials for Liquid Biopsy Profiling
by: Sabrina Weber, et al.
Published: (2020-06-01)

Putative Origins of Cell-Free DNA in Humans: A Review of Active and Passive Nucleic Acid Release Mechanisms
by: Stefan Grabuschnig, et al.
Published: (2020-10-01)

Clinical Validity of Circulating Tumor DNA as Prognostic and Predictive Marker for Personalized Colorectal Cancer Patient Management
by: Ariane Hallermayr, et al.
Published: (2022-02-01)

Pre-Analytical Evaluation of Streck Cell-Free DNA Blood Collection Tubes for Liquid Profiling in Oncology
by: Inga Medina Diaz, et al.
Published: (2023-03-01)

Clinical Application of Next-Generation Sequencing of Plasma Cell-Free DNA for Genotyping Untreated Advanced Non-Small Cell Lung Cancer
by: Maria Gabriela O. Fernandes, et al.
Published: (2021-05-01)

Machine-Learning-Based Clinical Biomarker Using Cell-Free DNA for Hepatocellular Carcinoma (HCC)
by: Taehee Lee, et al.
Published: (2022-04-01)

The potential for liquid biopsies in the precision medical treatment of breast cancer
by: Victoria A. Forte, et al.
Published: (2016-03-01)

Translational Utility of Liquid Biopsies in Thyroid Cancer Management
by: Ayanthi A. Wijewardene, et al.
Published: (2021-07-01)

Circulating tumor cells and their role in prostate cancer
by: Moritz Maas, et al.
Published: (2019-01-01)

Transcending Blood—Opportunities for Alternate Liquid Biopsies in Oncology
by: Bonnita Werner, et al.
Published: (2022-03-01)

Circulating Tumour DNA as Biomarker for Colorectal Liver Metastases: A Systematic Review and Meta-Analysis
by: Lissa Wullaert, et al.
Published: (2023-10-01)

Tekočinska biopsija pri raku
by: Tanja Jesenko, et al.
Published: (2018-09-01)

The Emerging Role of Liquid Biopsy in Gastric Cancer
by: Csongor György Lengyel, et al.
Published: (2021-05-01)

Individualized Mini-Panel Sequencing of ctDNA Allows Tumor Monitoring in Complex Karyotype Sarcomas
by: David Braig, et al.
Published: (2022-09-01)

Circulating Cell-Free DNA-Based Methylation Pattern in Saliva for Early Diagnosis of Head and Neck Cancer
by: Natalia Birknerova, et al.
Published: (2022-10-01)

Circulating tumour DNA as biomarker for rectal cancer: A systematic review and meta-analyses
by: Jan M. van Rees, et al.
Published: (2023-01-01)

From Pediatric to Adult Brain Cancer: Exploring Histone H3 Mutations in Australian Brain Cancer Patients
by: Benedicte Grebstad Tune, et al.
Published: (2023-10-01)