IRF3 Activation in Mast Cells Promotes FcεRI-Mediated Allergic Inflammation

IRF3 Activation in Mast Cells Promotes FcεRI-Mediated Allergic Inflammation

(1) Background: This study aims to elucidate a novel non-transcriptional action of IRF3 in addition to its role as a transcription factor in mast cell activation and associated allergic inflammation; (2) Methods: For in vitro experiments, mouse bone-marrow-derived mast cells (mBMMCs) and a rat basop...

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Bibliographic Details
Main Authors: Young-Ae Choi, Hima Dhakal, Soyoung Lee, Namkyung Kim, Byungheon Lee, Taeg Kyu Kwon, Dongwoo Khang, Sang-Hyun Kim
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Cells
Subjects:
allergic inflammation
histamine
histidine decarboxylase
interferon regulatory factor 3
mast cells
Online Access:https://www.mdpi.com/2073-4409/12/11/1493

Internet

https://www.mdpi.com/2073-4409/12/11/1493

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