Optical Imaging of Paramagnetic Bead-DNA Aggregation Inhibition Allows for Low Copy Number Detection of Infectious Pathogens.

Optical Imaging of Paramagnetic Bead-DNA Aggregation Inhibition Allows for Low Copy Number Detection of Infectious Pathogens.

DNA-paramagnetic silica bead aggregation in a rotating magnetic field facilitates the quantification of DNA with femtogram sensitivity, but yields no sequence-specific information. Here we provide an original description of aggregation inhibition for the detection of DNA and RNA in a sequence-specif...

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Bibliographic Details
Main Authors: Jacquelyn A DuVall, Juliane C Borba, Nazly Shafagati, Deborah Luzader, Nishant Shukla, Jingyi Li, Kylene Kehn-Hall, Melissa M Kendall, Sanford H Feldman, James P Landers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4466016?pdf=render

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