Antitumor Activity of Simvastatin in Preclinical Models of Mantle Cell Lymphoma

Antitumor Activity of Simvastatin in Preclinical Models of Mantle Cell Lymphoma

Background: Mantle cell lymphoma (MCL) is a rare and aggressive subtype of B-cell non-Hodgkin lymphoma that remains incurable with standard therapy. Statins are well-tolerated, inexpensive, and widely prescribed as cholesterol-lowering agents to treat hyperlipidemia and to prevent cardiovascular dis...

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Bibliographic Details
Main Authors: Juliana Carvalho Santos, Núria Profitós-Pelejà, Marcelo Lima Ribeiro, Gaël Roué
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cancers
Subjects:
statins
mantle cell lymphoma
cell proliferation
cell death
Online Access:https://www.mdpi.com/2072-6694/14/22/5601

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