The Relationship between Processing Speed and Regional White Matter Volume in Healthy Young People.
Processing speed is considered a key cognitive resource and it has a crucial role in all types of cognitive performance. Some researchers have hypothesised the importance of white matter integrity in the brain for processing speed; however, the relationship at the whole-brain level between white mat...
| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2015-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4580478?pdf=render |
| _version_ | 1818508527611674624 |
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| author | Daniele Magistro Hikaru Takeuchi Keyvan Kashkouli Nejad Yasuyuki Taki Atsushi Sekiguchi Rui Nouchi Yuka Kotozaki Seishu Nakagawa Carlos Makoto Miyauchi Kunio Iizuka Ryoichi Yokoyama Takamitsu Shinada Yuki Yamamoto Sugiko Hanawa Tsuyoshi Araki Hiroshi Hashizume Yuko Sassa Ryuta Kawashima |
| author_facet | Daniele Magistro Hikaru Takeuchi Keyvan Kashkouli Nejad Yasuyuki Taki Atsushi Sekiguchi Rui Nouchi Yuka Kotozaki Seishu Nakagawa Carlos Makoto Miyauchi Kunio Iizuka Ryoichi Yokoyama Takamitsu Shinada Yuki Yamamoto Sugiko Hanawa Tsuyoshi Araki Hiroshi Hashizume Yuko Sassa Ryuta Kawashima |
| author_sort | Daniele Magistro |
| collection | DOAJ |
| description | Processing speed is considered a key cognitive resource and it has a crucial role in all types of cognitive performance. Some researchers have hypothesised the importance of white matter integrity in the brain for processing speed; however, the relationship at the whole-brain level between white matter volume (WMV) and processing speed relevant to the modality or problem used in the task has never been clearly evaluated in healthy people. In this study, we used various tests of processing speed and Voxel-Based Morphometry (VBM) analyses, it is involves a voxel-wise comparison of the local volume of gray and white, to assess the relationship between processing speed and regional WMV (rWMV). We examined the association between processing speed and WMV in 887 healthy young adults (504 men and 383 women; mean age, 20.7 years, SD, 1.85). We performed three different multiple regression analyses: we evaluated rWMV associated with individual differences in the simple processing speed task, word-colour and colour-word tasks (processing speed tasks with words) and the simple arithmetic task, after adjusting for age and sex. The results showed a positive relationship at the whole-brain level between rWMV and processing speed performance. In contrast, the processing speed performance did not correlate with rWMV in any of the regions examined. Our results support the idea that WMV is associated globally with processing speed performance regardless of the type of processing speed task. |
| first_indexed | 2024-12-10T22:33:09Z |
| format | Article |
| id | doaj.art-50221bdb72a44c18a8e7ab766c7c64dc |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-10T22:33:09Z |
| publishDate | 2015-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-50221bdb72a44c18a8e7ab766c7c64dc2022-12-22T01:31:00ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-01109e013638610.1371/journal.pone.0136386The Relationship between Processing Speed and Regional White Matter Volume in Healthy Young People.Daniele MagistroHikaru TakeuchiKeyvan Kashkouli NejadYasuyuki TakiAtsushi SekiguchiRui NouchiYuka KotozakiSeishu NakagawaCarlos Makoto MiyauchiKunio IizukaRyoichi YokoyamaTakamitsu ShinadaYuki YamamotoSugiko HanawaTsuyoshi ArakiHiroshi HashizumeYuko SassaRyuta KawashimaProcessing speed is considered a key cognitive resource and it has a crucial role in all types of cognitive performance. Some researchers have hypothesised the importance of white matter integrity in the brain for processing speed; however, the relationship at the whole-brain level between white matter volume (WMV) and processing speed relevant to the modality or problem used in the task has never been clearly evaluated in healthy people. In this study, we used various tests of processing speed and Voxel-Based Morphometry (VBM) analyses, it is involves a voxel-wise comparison of the local volume of gray and white, to assess the relationship between processing speed and regional WMV (rWMV). We examined the association between processing speed and WMV in 887 healthy young adults (504 men and 383 women; mean age, 20.7 years, SD, 1.85). We performed three different multiple regression analyses: we evaluated rWMV associated with individual differences in the simple processing speed task, word-colour and colour-word tasks (processing speed tasks with words) and the simple arithmetic task, after adjusting for age and sex. The results showed a positive relationship at the whole-brain level between rWMV and processing speed performance. In contrast, the processing speed performance did not correlate with rWMV in any of the regions examined. Our results support the idea that WMV is associated globally with processing speed performance regardless of the type of processing speed task.http://europepmc.org/articles/PMC4580478?pdf=render |
| spellingShingle | Daniele Magistro Hikaru Takeuchi Keyvan Kashkouli Nejad Yasuyuki Taki Atsushi Sekiguchi Rui Nouchi Yuka Kotozaki Seishu Nakagawa Carlos Makoto Miyauchi Kunio Iizuka Ryoichi Yokoyama Takamitsu Shinada Yuki Yamamoto Sugiko Hanawa Tsuyoshi Araki Hiroshi Hashizume Yuko Sassa Ryuta Kawashima The Relationship between Processing Speed and Regional White Matter Volume in Healthy Young People. PLoS ONE |
| title | The Relationship between Processing Speed and Regional White Matter Volume in Healthy Young People. |
| title_full | The Relationship between Processing Speed and Regional White Matter Volume in Healthy Young People. |
| title_fullStr | The Relationship between Processing Speed and Regional White Matter Volume in Healthy Young People. |
| title_full_unstemmed | The Relationship between Processing Speed and Regional White Matter Volume in Healthy Young People. |
| title_short | The Relationship between Processing Speed and Regional White Matter Volume in Healthy Young People. |
| title_sort | relationship between processing speed and regional white matter volume in healthy young people |
| url | http://europepmc.org/articles/PMC4580478?pdf=render |
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