The prevention of diabetic cardiomyopathy by non-mitogenic acidic fibroblast growth factor is probably mediated by the suppression of oxidative stress and damage.

The prevention of diabetic cardiomyopathy by non-mitogenic acidic fibroblast growth factor is probably mediated by the suppression of oxidative stress and damage.

BACKGROUND: Emerging evidence showed the beneficial effect of acidic fibroblast growth factor (aFGF) on heart diseases. The present study investigated whether non-mitogenic aFGF (nm-aFGF) can prevent diabetic cardiomyopathy and the underlying mechanisms, if any. METHODOLOGY/PRINCIPAL FINDINGS: Type...

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Bibliographic Details
Main Authors: Chi Zhang, Linbo Zhang, Shali Chen, Biao Feng, Xuemian Lu, Yang Bai, Guang Liang, Yi Tan, Minglong Shao, Melissa Skibba, Litai Jin, Xiaokun Li, Subrata Chakrabarti, Lu Cai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3857250?pdf=render

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