Whole-proteome structures shed new light on posttranslational modifications.
Accurate but protein-only AlphaFold models may show structural fingerprints of likely posttranslational modifications (PTMs). In this issue of PLOS Biology, Bludau and colleagues add a functional context to models by combining them with readily available proteomics results.
Main Authors: | Robbie P Joosten, Jon Agirre |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-05-01
|
Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.3001673 |
Similar Items
-
The structural context of posttranslational modifications at a proteome-wide scale.
by: Isabell Bludau, et al.
Published: (2022-05-01) -
Integrative Proteomic Analysis of Multiple Posttranslational Modifications in Inflammatory Response
by: Feiyang Ji, et al.
Published: (2022-02-01) -
Impact of posttranslational modifications on atomistic structure of fibrinogen.
by: Žofie Sovová, et al.
Published: (2020-01-01) -
Posttranslational modifications in pathogenesis of PCOS
by: Huimei Wei, et al.
Published: (2022-10-01) -
Biosynthesis and Posttranslational Modification of Proteins /
by: Monson, Leda, author 652537, et al.
Published: (2012)