Pharmacokinetic considerations for enhancing drug repurposing opportunities of anthelmintics: Niclosamide as a case study

Pharmacokinetic considerations for enhancing drug repurposing opportunities of anthelmintics: Niclosamide as a case study

Recently, anthelmintics have showcased versatile therapeutic potential in addressing various diseases, positioning them as promising candidates for drug repurposing. However, challenges such as low bioavailability and a lack of a solid pharmacokinetic basis impede successful repurposing. To overcome...

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Bibliographic Details
Main Authors: Jeong In Seo, Geun-woo Jin, Hye Hyun Yoo
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Drug repurposing
Niclosamide
Absorption
Metabolism
Drug-drug interactions
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224002786

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