Gestational diabetes mellitus: Yesterday, today, tomorrow

Gestational diabetes mellitus (GDM) is hyperglycemia that is first detected during pregnancy and does not meet the criteria for manifest diabetes. The incidence of GDM worldwide varies from 1 to 14% and that in Russia is as high as 4%. Hyperglycemia during pregnancy is associated with the developmen...

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Main Authors: F F Burumkulova, V A Petrukhin
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2014-10-01
Series:Терапевтический архив
Subjects:
Online Access:https://ter-arkhiv.ru/0040-3660/article/view/31627
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author F F Burumkulova
V A Petrukhin
author_facet F F Burumkulova
V A Petrukhin
author_sort F F Burumkulova
collection DOAJ
description Gestational diabetes mellitus (GDM) is hyperglycemia that is first detected during pregnancy and does not meet the criteria for manifest diabetes. The incidence of GDM worldwide varies from 1 to 14% and that in Russia is as high as 4%. Hyperglycemia during pregnancy is associated with the development of preeclampsia, the birth of a big baby, emergency cesarean section, birth trauma, and neonatal hypoglycemia. The fact that there is no well-organized screening for GDM in our country leads to that the diagnosis of this condition is delayed for 4-20 weeks in 50-60% of cases. The risk group distribution of pregnant women leads to the diagnosis of GDM only in 50% of cases. At the same time, pregnancy is accompanied by physiological insulin resistance so the latter itself is a clinically important risk factor for carbohydrate metabolic disturbances. The Hyperglycemia and Adverse Pregnancy Outcomes (HYPO) study has indicated that the previously used diagnostic criteria for GDM require reconsideration. There is a need for uniform standards for the diagnosis and treatment of carbohydrate metabolic disturbances during pregnancy. The concepts "diabetes mellitus (DM)" and "manifest (new-onset DM during pregnancy" and directly "GDM" require clear clinical and laboratory definitions. Furthermore, GDM is a risk factor for obesity, type 2 DM and cardiovascular diseases in the mother and her offspring in future.
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spelling doaj.art-5024a741e434400e88467eaff9bb02f02022-12-21T19:18:18Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422014-10-01861010911528643Gestational diabetes mellitus: Yesterday, today, tomorrowF F BurumkulovaV A PetrukhinGestational diabetes mellitus (GDM) is hyperglycemia that is first detected during pregnancy and does not meet the criteria for manifest diabetes. The incidence of GDM worldwide varies from 1 to 14% and that in Russia is as high as 4%. Hyperglycemia during pregnancy is associated with the development of preeclampsia, the birth of a big baby, emergency cesarean section, birth trauma, and neonatal hypoglycemia. The fact that there is no well-organized screening for GDM in our country leads to that the diagnosis of this condition is delayed for 4-20 weeks in 50-60% of cases. The risk group distribution of pregnant women leads to the diagnosis of GDM only in 50% of cases. At the same time, pregnancy is accompanied by physiological insulin resistance so the latter itself is a clinically important risk factor for carbohydrate metabolic disturbances. The Hyperglycemia and Adverse Pregnancy Outcomes (HYPO) study has indicated that the previously used diagnostic criteria for GDM require reconsideration. There is a need for uniform standards for the diagnosis and treatment of carbohydrate metabolic disturbances during pregnancy. The concepts "diabetes mellitus (DM)" and "manifest (new-onset DM during pregnancy" and directly "GDM" require clear clinical and laboratory definitions. Furthermore, GDM is a risk factor for obesity, type 2 DM and cardiovascular diseases in the mother and her offspring in future.https://ter-arkhiv.ru/0040-3660/article/view/31627pregnancygestational diabetes mellitusdiabetic fetopathymacrosomiagestosisinsulin
spellingShingle F F Burumkulova
V A Petrukhin
Gestational diabetes mellitus: Yesterday, today, tomorrow
Терапевтический архив
pregnancy
gestational diabetes mellitus
diabetic fetopathy
macrosomia
gestosis
insulin
title Gestational diabetes mellitus: Yesterday, today, tomorrow
title_full Gestational diabetes mellitus: Yesterday, today, tomorrow
title_fullStr Gestational diabetes mellitus: Yesterday, today, tomorrow
title_full_unstemmed Gestational diabetes mellitus: Yesterday, today, tomorrow
title_short Gestational diabetes mellitus: Yesterday, today, tomorrow
title_sort gestational diabetes mellitus yesterday today tomorrow
topic pregnancy
gestational diabetes mellitus
diabetic fetopathy
macrosomia
gestosis
insulin
url https://ter-arkhiv.ru/0040-3660/article/view/31627
work_keys_str_mv AT ffburumkulova gestationaldiabetesmellitusyesterdaytodaytomorrow
AT vapetrukhin gestationaldiabetesmellitusyesterdaytodaytomorrow