Cloning, Expression Analysis and Functional Characterization of Squalene Synthase (SQS) from Tripterygium wilfordii

Cloning, Expression Analysis and Functional Characterization of Squalene Synthase (SQS) from Tripterygium wilfordii

Celastrol is an active triterpenoid compound derived from Tripterygium wilfordii which is well-known as a traditional Chinese medicinal plant. Squalene synthase has a vital role in condensing two molecules of farnesyl diphosphate to form squalene, a key precursor of triterpenoid biosynthesis. In the...

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Bibliographic Details
Main Authors: Bin Zhang, Yan Liu, Mengmeng Chen, Juntao Feng, Zhiqing Ma, Xing Zhang, Chuanshu Zhu
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Molecules
Subjects:
Tripterygium wilfordii
squalene synthase
celastrol
prokaryotic expression
functional characterization
Online Access:http://www.mdpi.com/1420-3049/23/2/269

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