Early Exercise Training After Renal Transplantation and Asymmetric Dimethylarginine: The Effect of Obesity
Background/Aims: To assess, in a prospective cohort study of 238 renal transplant patients, our hypothesis that elevated ADMA levels may be influenced by physical exercise and obesity. Methods: Blood samples before and after six months were obtained from 116 transplant patients participating in an a...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2014-08-01
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| Series: | Kidney & Blood Pressure Research |
| Subjects: | |
| Online Access: | http://www.karger.com/Article/FullText/355806 |
| _version_ | 1828853270632726528 |
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| author | Vladimír Teplan Andrea Mahrova Jan Piťha Jaroslav Racek Robert Gürlich Vladimír Teplan Jr Ivo Valkovsky Milena Štollova |
| author_facet | Vladimír Teplan Andrea Mahrova Jan Piťha Jaroslav Racek Robert Gürlich Vladimír Teplan Jr Ivo Valkovsky Milena Štollova |
| author_sort | Vladimír Teplan |
| collection | DOAJ |
| description | Background/Aims: To assess, in a prospective cohort study of 238 renal transplant patients, our hypothesis that elevated ADMA levels may be influenced by physical exercise and obesity. Methods: Blood samples before and after six months were obtained from 116 transplant patients participating in an aerobic exercise (Group I). A control group consisted of 122 matched transplant patients who did not exercise regularly (Group II). Results: There were no significant differences in ADMA levels between both groups before the training program (Group IB vs Group IIB). After six months of exercise, ADMA levels in Group I decreased (Group IB vs Group IA : 3.50 ± 0.45 vs 2.11 ± 0.35μmol/L; pA vs Group IIA : 2 11 ± 0 23 vs 3 25 ± 0 34μmol/L; p2) confirmed a smaller effect of exercise training (Group IBO vs Group IAO : 3 75 ± 0 52 vs 3 45 ± 0 45; pAO vs Group IIAO : 3.45 ± 0.45 vs 3.74 ± 0.62; p1C, insulin, and systolic BP were also affected by the training program. Conclusion: Elevated ADMA levels were significantly decreased by early exercise after renal transplantation. The effect of exercise was smaller in obese patients. |
| first_indexed | 2024-12-13T00:10:26Z |
| format | Article |
| id | doaj.art-50278f440da847968074563f7a9b2d37 |
| institution | Directory Open Access Journal |
| issn | 1420-4096 1423-0143 |
| language | English |
| last_indexed | 2024-12-13T00:10:26Z |
| publishDate | 2014-08-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Kidney & Blood Pressure Research |
| spelling | doaj.art-50278f440da847968074563f7a9b2d372022-12-22T00:06:00ZengKarger PublishersKidney & Blood Pressure Research1420-40961423-01432014-08-0139428929810.1159/000355806355806Early Exercise Training After Renal Transplantation and Asymmetric Dimethylarginine: The Effect of ObesityVladimír TeplanAndrea MahrovaJan PiťhaJaroslav RacekRobert GürlichVladimír Teplan JrIvo ValkovskyMilena ŠtollovaBackground/Aims: To assess, in a prospective cohort study of 238 renal transplant patients, our hypothesis that elevated ADMA levels may be influenced by physical exercise and obesity. Methods: Blood samples before and after six months were obtained from 116 transplant patients participating in an aerobic exercise (Group I). A control group consisted of 122 matched transplant patients who did not exercise regularly (Group II). Results: There were no significant differences in ADMA levels between both groups before the training program (Group IB vs Group IIB). After six months of exercise, ADMA levels in Group I decreased (Group IB vs Group IA : 3.50 ± 0.45 vs 2.11 ± 0.35μmol/L; pA vs Group IIA : 2 11 ± 0 23 vs 3 25 ± 0 34μmol/L; p2) confirmed a smaller effect of exercise training (Group IBO vs Group IAO : 3 75 ± 0 52 vs 3 45 ± 0 45; pAO vs Group IIAO : 3.45 ± 0.45 vs 3.74 ± 0.62; p1C, insulin, and systolic BP were also affected by the training program. Conclusion: Elevated ADMA levels were significantly decreased by early exercise after renal transplantation. The effect of exercise was smaller in obese patients.http://www.karger.com/Article/FullText/355806Physical ExerciseRenal TransplantationADMAObesity |
| spellingShingle | Vladimír Teplan Andrea Mahrova Jan Piťha Jaroslav Racek Robert Gürlich Vladimír Teplan Jr Ivo Valkovsky Milena Štollova Early Exercise Training After Renal Transplantation and Asymmetric Dimethylarginine: The Effect of Obesity Kidney & Blood Pressure Research Physical Exercise Renal Transplantation ADMA Obesity |
| title | Early Exercise Training After Renal Transplantation and Asymmetric Dimethylarginine: The Effect of Obesity |
| title_full | Early Exercise Training After Renal Transplantation and Asymmetric Dimethylarginine: The Effect of Obesity |
| title_fullStr | Early Exercise Training After Renal Transplantation and Asymmetric Dimethylarginine: The Effect of Obesity |
| title_full_unstemmed | Early Exercise Training After Renal Transplantation and Asymmetric Dimethylarginine: The Effect of Obesity |
| title_short | Early Exercise Training After Renal Transplantation and Asymmetric Dimethylarginine: The Effect of Obesity |
| title_sort | early exercise training after renal transplantation and asymmetric dimethylarginine the effect of obesity |
| topic | Physical Exercise Renal Transplantation ADMA Obesity |
| url | http://www.karger.com/Article/FullText/355806 |
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