Messing Up the Cancer Stem Cell Chemoresistance Mechanisms Supported by Tumor Microenvironment

Messing Up the Cancer Stem Cell Chemoresistance Mechanisms Supported by Tumor Microenvironment

Despite the recent advances in cancer patient management and in the development of targeted therapies, systemic chemotherapy is currently used as a first-line treatment for many cancer types. After an initial partial response, patients become refractory to standard therapy fostering rapid tumor prog...

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Bibliographic Details
Main Authors: Miriam Gaggianesi, Simone Di Franco, Vincenzo Davide Pantina, Gaetana Porcelli, Caterina D'Accardo, Francesco Verona, Veronica Veschi, Lorenzo Colarossi, Naida Faldetta, Giuseppe Pistone, Maria Rita Bongiorno, Matilde Todaro, Giorgio Stassi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Oncology
Subjects:
cancer stem cells
tumor microenvironment
anticancer drugs
chemoresistance
targeted therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.702642/full

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