Clostridium difficile bacteremia and meningitis as a complication of prolonged cephalosporin therapy in a case of staphylococcal pyogenic arthritis
With increasing incidence of Clostridium difficile (C. difficile) associated diarrhea and pseudomembranous colitis, several extra-intestinal manifestations of the organism have been unmasked which include-bacteremia, brain abscess, pericarditis etc. We report a rare and interesting case of C. diffic...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2012-01-01
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| Series: | Journal of Acute Disease |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2221618913600402 |
| _version_ | 1819260717626294272 |
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| author | Abhrajit Ganguly Saibal Das Jayanta Kumar Dey Somnath Mondal |
| author_facet | Abhrajit Ganguly Saibal Das Jayanta Kumar Dey Somnath Mondal |
| author_sort | Abhrajit Ganguly |
| collection | DOAJ |
| description | With increasing incidence of Clostridium difficile (C. difficile) associated diarrhea and pseudomembranous colitis, several extra-intestinal manifestations of the organism have been unmasked which include-bacteremia, brain abscess, pericarditis etc. We report a rare and interesting case of C. difficile bacteremia and subsequent meningitis in a 10 year old child. The child was immune competent, which further raises the question about the virulent possibilities of the organism and its implications in the near future. The condition resulted from a prolonged treatment with intravenous (I.V.) cefotaxime for staphylococcal pyogenic arthritis. The child recovered from the septic arthritis but on the 7th day post-admission developed features of bacteremia. The child was later treated with intravenous metronidazole and vancomycin and he was discharged on the 21st day post-admission. No recurrence of symptoms was noted. |
| first_indexed | 2024-12-23T19:30:21Z |
| format | Article |
| id | doaj.art-502dd96607f646958a535c2957373cbd |
| institution | Directory Open Access Journal |
| issn | 2221-6189 |
| language | English |
| last_indexed | 2024-12-23T19:30:21Z |
| publishDate | 2012-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Acute Disease |
| spelling | doaj.art-502dd96607f646958a535c2957373cbd2022-12-21T17:33:56ZengWolters Kluwer Medknow PublicationsJournal of Acute Disease2221-61892012-01-011215916110.1016/S2221-6189(13)60040-2Clostridium difficile bacteremia and meningitis as a complication of prolonged cephalosporin therapy in a case of staphylococcal pyogenic arthritisAbhrajit Ganguly0Saibal Das1Jayanta Kumar Dey2Somnath Mondal3Department of Pediatrics Medicine, N.R.S. Medical College and Hospital, Kolkata 700 014, IndiaGeneral Emergency, N.R.S. Medical College and Hospital, Kolkata 700 014, IndiaDepartment of Ophthalmology, N.R.S. Medical College and Hospital, Kolkata 700 014, IndiaADR Monitoring Center, Indian Pharmacy Council (IPC), Ghaziabad Drug Control General of IndiaWith increasing incidence of Clostridium difficile (C. difficile) associated diarrhea and pseudomembranous colitis, several extra-intestinal manifestations of the organism have been unmasked which include-bacteremia, brain abscess, pericarditis etc. We report a rare and interesting case of C. difficile bacteremia and subsequent meningitis in a 10 year old child. The child was immune competent, which further raises the question about the virulent possibilities of the organism and its implications in the near future. The condition resulted from a prolonged treatment with intravenous (I.V.) cefotaxime for staphylococcal pyogenic arthritis. The child recovered from the septic arthritis but on the 7th day post-admission developed features of bacteremia. The child was later treated with intravenous metronidazole and vancomycin and he was discharged on the 21st day post-admission. No recurrence of symptoms was noted.http://www.sciencedirect.com/science/article/pii/S2221618913600402BacteremiaMeningitisCephalosporinPyogenic arthritis |
| spellingShingle | Abhrajit Ganguly Saibal Das Jayanta Kumar Dey Somnath Mondal Clostridium difficile bacteremia and meningitis as a complication of prolonged cephalosporin therapy in a case of staphylococcal pyogenic arthritis Journal of Acute Disease Bacteremia Meningitis Cephalosporin Pyogenic arthritis |
| title | Clostridium difficile bacteremia and meningitis as a complication of prolonged cephalosporin therapy in a case of staphylococcal pyogenic arthritis |
| title_full | Clostridium difficile bacteremia and meningitis as a complication of prolonged cephalosporin therapy in a case of staphylococcal pyogenic arthritis |
| title_fullStr | Clostridium difficile bacteremia and meningitis as a complication of prolonged cephalosporin therapy in a case of staphylococcal pyogenic arthritis |
| title_full_unstemmed | Clostridium difficile bacteremia and meningitis as a complication of prolonged cephalosporin therapy in a case of staphylococcal pyogenic arthritis |
| title_short | Clostridium difficile bacteremia and meningitis as a complication of prolonged cephalosporin therapy in a case of staphylococcal pyogenic arthritis |
| title_sort | clostridium difficile bacteremia and meningitis as a complication of prolonged cephalosporin therapy in a case of staphylococcal pyogenic arthritis |
| topic | Bacteremia Meningitis Cephalosporin Pyogenic arthritis |
| url | http://www.sciencedirect.com/science/article/pii/S2221618913600402 |
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