MKRN2 knockout causes male infertility through decreasing STAT1, SIX4, and TNC expression

MKRN2 knockout causes male infertility through decreasing STAT1, SIX4, and TNC expression

Makorin-2 (Mkrn2) is an evolutionarily conserved gene whose biological functions are not fully known. Although recent studies have shed insights on the potential causes of male infertility, its underlining mechanisms still remain to be elucidated. We developed a Mrkn2 knockout mice model to study th...

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Bibliographic Details
Main Authors: Lin Wang, Yan-Ling Yong, Kun-Kun Wang, Yun-Xia Xie, Ying-Chen Qian, Feng-Mei Zhou, Jian-Ge Qiu, Bing-Hua Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Endocrinology
Subjects:
MKRN2
STAT1
SIX4
TNC
male infertility
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1138096/full

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