Frequent Occurrence of <i>NRAS</i> and <i>BRAF</i> Mutations in Human Acral Naevi

Frequent Occurrence of <i>NRAS</i> and <i>BRAF</i> Mutations in Human Acral Naevi

Acral naevi are benign melanocytic tumors occurring at acral sites. Occasionally they can progress to become malignant tumors (melanomas). The genetics of acral naevi have not been assessed in larger studies. In our study, a large cohort of 130 acral naevi was screened for gene mutations known to be...

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Bibliographic Details
Main Authors: Philipp Jansen, Ioana Cosgarea, Rajmohan Murali, Inga Möller, Antje Sucker, Cindy Franklin, Annette Paschen, Anne Zaremba, Titus J. Brinker, Ingo Stoffels, Dirk Schadendorf, Joachim Klode, Eva Hadaschik, Klaus G. Griewank
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cancers
Subjects:
acral
naevi
melanoma
genetics
dermatology
Online Access:https://www.mdpi.com/2072-6694/11/4/546

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